Reséndiz-Aparicio J C, Ruiz-García M, Castro-Martínez E
Hospital Psiquiátrico Infantil Dr. Juan N. Navarro, Ciudad de México, México.
Instituto Nacional de Neurologia y Neurocirugia "Dr. Manuel Velasco Suárez", Ciudad de México, México.
Rev Neurol. 2024 Jan 1;78(1):9-15. doi: 10.33588/rn.7801.2023296.
The National Epilepsy Registry in Mexico was carried out, from March 2021 to December 2022, in public hospitals of the Priority Epilepsy Program 'PPE', with the aim of describing the current situation in our pediatric and adult population.
Observational, cross-sectional, multicenter study. We used a database, according to classifications of the International League Against Epilepsy (ILAE) 2017. Patients of all ages were included, with a diagnosis of epilepsy according to the practical clinical definition ILAE 2014.
We registered 10,852 patients, 5,495 men (50.6%) and 5,357 women (49.4%). Family history of epilepsy in 1,714 patients (15.8%), febrile seizures in 987 (9.1%). Type of seizure: 5,542 (51.1%) presented focal onset, of which 1,889 (34.1%) evolved to bilateral tonic-clonic seizures; generalized onset 4,861 (44.8%), unknown 33 (3.1%) and unclassified 115 (1.1%). Almost half had unknown etiology and 40% were structural, of which hypoxic ischemic encephalopathy was the most frequent (21.6%) and neurocysticercosis was 1%. Comorbidities appeared in 6,326 patients (58.3%). Anti-seizure medications (ASM) were used in 96.4% patients, mainly valproate. Status epilepticus was found in 1,383 patients (12.7%) and drug-resistant epilepsy in 18.9%. Paraclinical studies: 79.3% with at least one electroencephalogram and 76.9% with a neuroimaging study. Epilepsy surgery occurred in 275 patients (2.5%).
Despite the efforts of the Pan American Health Organization in its Strategy and Action Plan on epilepsy, diagnostic technologies and ASM supply are still lagging behind.
墨西哥国家癫痫登记处于2021年3月至2022年12月在“优先癫痫项目”(PPE)的公立医院开展,旨在描述我国儿童和成人的癫痫现状。
观察性、横断面、多中心研究。我们根据国际抗癫痫联盟(ILAE)2017年的分类使用了一个数据库。纳入了所有年龄段的患者,根据ILAE 2014年实用临床定义诊断为癫痫。
我们登记了10852名患者,其中男性5495名(50.6%),女性5357名(49.4%)。1714名患者(15.8%)有癫痫家族史,987名(9.1%)有热性惊厥史。发作类型:5542名(51.1%)为局灶性发作,其中1889名(34.1%)演变为双侧强直阵挛发作;全身性发作4861名(44.8%),不明33名(3.1%),未分类115名(1.1%)。近一半病因不明,40%为结构性病因,其中缺氧缺血性脑病最为常见(21.6%),神经囊尾蚴病为1%。6326名患者(58.3%)出现合并症。96.4%的患者使用了抗癫痫药物(ASM),主要是丙戊酸盐。1383名患者(12.7%)出现癫痫持续状态,18.9%为药物难治性癫痫。辅助检查:79.3%至少进行了一次脑电图检查,76.9%进行了神经影像学检查。275名患者(2.5%)接受了癫痫手术。
尽管泛美卫生组织在其癫痫战略和行动计划方面做出了努力,但诊断技术和抗癫痫药物供应仍滞后。