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[自由基氧化过程在再生神经轴突形态发生中的作用]

[The role of free radical oxidation processes in the morphogenesis of axons of regenerating nerves].

作者信息

Radlinskaia V N, Voskresenskiĭ O N, Bobyrev V N, Zhutaev I A

出版信息

Vopr Med Khim. 1986 Nov-Dec;32(6):58-60.

PMID:3811288
Abstract

Patterns of lipid peroxidation as well as morphogenesis and differentiation of newly formed axons in regenerating nerve were studied in guinea pigs with experimental syndrome of peroxidation which developed after local gamma-irradiation of right hind legs of the animals maintained on the diet containing no antioxidants. The diet without antioxidants increased the inhibitory and impairing effects of the radiation on differentiation of the regenerating nerve and also caused similar effects in control experiments without the irradiation.

摘要

在豚鼠身上研究了脂质过氧化模式以及再生神经中新形成轴突的形态发生和分化。这些豚鼠因接受局部γ射线照射而出现过氧化实验综合征,它们被饲养在不含抗氧化剂的饮食中,照射部位为动物的右后腿。不含抗氧化剂的饮食增强了辐射对再生神经分化的抑制和损害作用,并且在未进行辐射的对照实验中也产生了类似影响。

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