Keeler K D, Phillips J M, Dresser D W
Immunology. 1979 May;37(1):263-71.
Anti-allotype sera have shown a breakdown of the expected specificity especially when used for the development of haemolysis of fragile target erythrocytes. IgM anti-IgG rheumatoid factor has been shown to be the source of non-specificity. Removal or destruction of IgM in an anti-allotype serum restores the expected specificity.
抗同种异型血清已显示出预期特异性的破坏,尤其是当用于诱导脆弱靶红细胞溶血时。IgM抗IgG类风湿因子已被证明是非特异性的来源。在抗同种异型血清中去除或破坏IgM可恢复预期的特异性。