Korpela M, Mustonen J, Pasternack A, Leinikki P
Acta Med Scand. 1986;220(5):471-6. doi: 10.1111/j.0954-6820.1986.tb02797.x.
We studied 71 patients with acute Yersinia infection for the occurrence of pathologic urinary and renal findings. Transient proteinuria and/or microhematuria was found in 17 patients (24%) and slightly elevated serum creatinine in seven patients (10%). Renal biopsy was done in two patients and revealed mild mesangial glomerulonephritis in both cases. One of these patients had IgA glomerulonephritis and Reiter's syndrome. Pyuria occurred in 16 patients (23%) and was frequently associated with Reiter's syndrome. Seventy-three patients with acute intrinsic renal failure were studied for the occurrence of acute Yersinia infection by determining Yersinia antibodies by ELISA. One out of 13 patients with acute glomerulonephritis but none of 60 patients with acute tubulointerstitial renal disease had acute Yersinia infection. Acute Yersinia infection seems to be rarely an etiologic factor in acute intrinsic renal failure. Our results indicate that transient proteinuria, microhematuria, pyuria or impaired renal function are frequent findings in patients with acute Yersinia infections. However, glomerulonephritis seems to be a rather infrequent and mild complication of acute Yersinia infection.
我们研究了71例急性耶尔森菌感染患者，以观察病理性尿液和肾脏检查结果的发生情况。17例患者（24%）发现有短暂性蛋白尿和/或微量血尿，7例患者（10%）血清肌酐略有升高。对2例患者进行了肾活检，两例均显示轻度系膜增生性肾小球肾炎。其中1例患者患有IgA肾病和赖特综合征。16例患者（23%）出现脓尿，且常与赖特综合征相关。通过ELISA法检测耶尔森菌抗体，研究了73例急性肾衰患者急性耶尔森菌感染的发生情况。13例急性肾小球肾炎患者中有1例发生急性耶尔森菌感染，而60例急性肾小管间质性肾病患者中无一例发生感染。急性耶尔森菌感染似乎很少是急性肾衰的病因。我们的结果表明，短暂性蛋白尿、微量血尿、脓尿或肾功能受损在急性耶尔森菌感染患者中很常见。然而，肾小球肾炎似乎是急性耶尔森菌感染较少见且较轻的并发症。
