在有胃肠道症状的 COVID-19 患者中未发现轮状病毒合并感染的迹象。
No sign of Rotavirus co-infection in COVID-19 patients with gastrointestinal symptoms.
机构信息
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Abadan University of Medical Sciences, Abadan, Iran.
出版信息
Malawi Med J. 2023 Mar;35(1):27-30. doi: 10.4314/mmj.v35i1.6.
BACKGROUND AND AIMS
The main goal of the present study is to investigate the incidence of Rotavirus co-infection in COVID-19 patients.
METHODS AND RESULTS
Fecal samples of COVID-19 patients with gastrointestinal symptoms which had positive PCR- were collected from Abadan's hospital, Iran during the period December 2020 to January 2021. Samples were analyzed by RT-PCR to determine the presence of Rotavirus. Finally, the total samples size of 37 were included in this study. The mean age of patients was 48.22 years. Abdominal pain alone was detected in 48.65% of the patients. At least one gastrointestinal symptom was detected in all of the patients. Diarrhea and fever were seen in 13.51% and 59.46% of patients, respectively. Nausea and vomiting were seen in 5.41% of the patients. RT-PCR showed no infection of Rotavirus among the patients.
CONCLUSION
Gastrointestinal symptoms related to COVID-19 are common. More studies is need among these patients groups for investigate co-infection with other fecal viral shedding carries, due to a worse prognosis and its association with disease severity.
背景与目的
本研究的主要目的是调查 COVID-19 患者中轮状病毒合并感染的发生率。
方法与结果
2020 年 12 月至 2021 年 1 月期间，从伊朗阿巴丹医院收集了具有胃肠道症状且 PCR 阳性的 COVID-19 患者的粪便样本。通过 RT-PCR 分析样本以确定轮状病毒的存在。最终，本研究共纳入 37 例样本。患者的平均年龄为 48.22 岁。48.65%的患者仅出现腹痛。所有患者均至少出现一种胃肠道症状。腹泻和发热分别见于 13.51%和 59.46%的患者，5.41%的患者出现恶心和呕吐。RT-PCR 显示患者中不存在轮状病毒感染。
结论
与 COVID-19 相关的胃肠道症状很常见。由于预后较差且与疾病严重程度相关，需要对这些患者群体进行其他肠道病毒脱落载体合并感染的研究。
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