现场 ready SARS-CoV-2 病毒诊断用生物传感器的未来发展。
Future developments in biosensors for field-ready SARS-CoV-2 virus diagnostics.
机构信息
School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Biotechnol Appl Biochem. 2021 Aug;68(4):695-699. doi: 10.1002/bab.2033. Epub 2020 Oct 19.
Abstract
According to the evidence, the coronavirus disease 19 (COVID-19) is caused by a zoonotic pathogen named respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus can spread through personal contact, respiratory droplets, and also through airborne transmission. A rapid, low-cost, and effective biosensor platform is essential to diagnose patients with COVID-19 infection, predominantly the asymptomatic individuals, and prevent the spread of the SARS-CoV-2 via transmission routes. The objective of this review is to provide a comparative view among current diagnostic methods, focusing on recently suggested biosensors for the detection of SARS-CoV2 in clinical samples. A capable SARS-CoV-2 biosensor can be designed by the holistic insights of various biosensor studies.
摘要
根据证据，2019 年冠状病毒病（COVID-19）是由一种名为严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的人畜共患病原体引起的。这种病毒可以通过人际接触、呼吸道飞沫传播，也可以通过空气传播。一个快速、低成本和有效的生物传感器平台对于诊断 COVID-19 感染患者，主要是无症状个体，以及通过传播途径预防 SARS-CoV-2 的传播至关重要。本综述的目的是提供当前诊断方法的比较观点，重点介绍最近提出的用于检测临床样本中 SARS-CoV2 的生物传感器。通过对各种生物传感器研究的整体了解，可以设计出一种有能力的 SARS-CoV-2 生物传感器。
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