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真菌毒素结合剂:对奶牛健康和生产性能的影响及降低牛奶中 AFM 残留的效果。

Mycotoxin sequestering agent: Impact on health and performance of dairy cows and efficacy in reducing AFM residues in milk.

机构信息

Instituto de Investigación de la Cadena Láctea (INTA-CONICET), Route 34, Km 227, 2300 Rafaela, Santa Fe, Argentina.

Estación Experimental Agropecuaria Rafaela - Instituto Nacional de Tecnología Agropecuaria (EEA Rafaela INTA), Route 34 Km 227, 2300 Rafaela, Santa Fe, Argentina.

出版信息

Environ Toxicol Pharmacol. 2024 Jan;105:104349. doi: 10.1016/j.etap.2023.104349. Epub 2023 Dec 21.

Abstract

The objectives of this study were to evaluate the exposure to a diet naturally contaminated with mycotoxins on lactation performance, animal health, and the ability to sequester agents (SA) to reduce the human exposure to AFM. Sixty healthy lactating Holstein cows were randomly assigned to two groups: naturally contaminated diet without and with the addition of a SA (20 g/cow/d AntitoxCooPil® -60% zeolite-40% cell wall-). Each cow was monitored throughout lactation. The concentration of aflatoxin B (AFB) in feed and M (AFM) in milk, health status, and productive and reproductive parameters were measured. AFB concentration in feed was very low (2.31 μg/kgDM). The addition of SA reduced the milk AFM concentrations (0.016 vs. 0.008 μg/kg) and transfer rates (2.19 vs. 0.77%). No differences were observed in health status, production and reproduction performance. The inclusion of SA in the diet of dairy cows reduce the risk in the most susceptible population.

摘要

本研究的目的是评估哺乳期奶牛接触天然污染霉菌毒素的情况,评估其对泌乳性能、动物健康以及结合(sequester)能力的影响,以降低人类接触 AFM 的风险。将 60 头健康的泌乳荷斯坦奶牛随机分为两组:未添加和添加结合剂(20 g/头/天 AntitoxCooPil®-60%沸石-40%细胞壁)的天然污染饮食。对每头奶牛进行了整个哺乳期的监测。测量了饲料中黄曲霉毒素 B(AFB)和牛奶中 M(AFM)的浓度、健康状况以及生产和繁殖参数。饲料中 AFB 的浓度非常低(2.31μg/kgDM)。添加结合剂降低了牛奶 AFM 浓度(0.016 对 0.008μg/kg)和转移率(2.19 对 0.77%)。健康状况、生产和繁殖性能没有差异。在奶牛饮食中添加结合剂降低了最易受影响人群的风险。

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