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老年痛风,一种独立的疾病?

Gout in the elderly, a separate entity?

作者信息

ter Borg E J, Rasker J J

出版信息

Ann Rheum Dis. 1987 Jan;46(1):72-6. doi: 10.1136/ard.46.1.72.

Abstract

To evaluate whether the clinical pattern of gout differed between elderly women and men a retrospective study was performed in all women (22) and men (18) in our rheumatological clinics who developed gout after the age of 60. The diagnosis was made after a mean of 2.6 years of joint complaints in women and after 1.2 years in men. In about half the patients complaints started in more than one joint, often including the big toe. In five women, but none of the men, complaints started in the fingers. No correlation was found between gout and the presence of tophi or Heberden's nodes in the finger joints. The mean uric acid level was higher in women (0.61 mmol/l) than in men (0.53 mmol/l), and almost all the women (95%) used diuretics and only 56% of the men did so.

摘要

为评估60岁后发生痛风的老年女性和男性的痛风临床模式是否存在差异,我们对风湿科门诊中所有60岁后发生痛风的女性(22例)和男性(18例)进行了一项回顾性研究。女性在出现关节症状平均2.6年后确诊痛风,男性则为1.2年后。约一半患者的症状始于多个关节,通常包括大脚趾。有5名女性的症状始于手指关节,但男性无一如此。痛风与手指关节中痛风石或赫伯登结节的存在之间未发现相关性。女性的平均尿酸水平(0.61 mmol/l)高于男性(0.53 mmol/l),几乎所有女性(95%)使用利尿剂,而男性仅为56%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5125/1002061/2ecf341f572e/annrheumd00280-0089-a.jpg

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