Coulehan J L, Zettler-Segal M, Block M, McClelland M, Schulberg H C
Arch Intern Med. 1987 Feb;147(2):349-52.
Alcohol and other substance abuse are frequently seen in primary medical practice but are underdiagnosed. Forty-two (14%) of 294 adult primary care patients suffered from alcohol or other substance abuse, as diagnosed by a structured psychiatric interview. Primary care physicians identified 17 (40%) of these patients, as well as another patient identified during a six-month follow-up period, as having a substance abuse problem at initial clinical evaluation. Clinically identified substance abusers were older, more likely to be married, and more often used multiple drugs. They more frequently had antisocial personality disorders, while patients not clinically recognized were often depressed. Logistic regression analysis indicated that the presence of antisocial personality, the absence of a coexisting depressive disorder, and better social functioning scores were the factors most strongly associated with clinical recognition. The study suggests clinical judgment issues, which may be useful to physicians in training to improve their recognition and treatment of substance abuse disorders.
酒精和其他物质滥用在初级医疗实践中很常见,但往往诊断不足。通过结构化精神科访谈诊断,294名成年初级保健患者中有42名(14%)患有酒精或其他物质滥用。初级保健医生在初次临床评估时识别出其中17名(40%)患者以及在六个月随访期间识别出的另一名患者存在物质滥用问题。临床识别出的物质滥用者年龄较大,更有可能已婚,且更常使用多种药物。他们更频繁地患有反社会人格障碍,而未被临床识别的患者往往患有抑郁症。逻辑回归分析表明,反社会人格的存在、不存在并存的抑郁症以及更好的社会功能评分是与临床识别最密切相关的因素。该研究提示了临床判断问题,这可能对接受培训的医生提高对物质滥用障碍的识别和治疗能力有用。