槲皮素：一种潜在的多动态药物。

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.

Laboratory of Organic Chemistry and Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece.

Molecules. 2023 Dec 17;28(24):8141. doi: 10.3390/molecules28248141.

The study of natural products as potential drug leads has gained tremendous research interest. Quercetin is one of those natural products. It belongs to the family of flavonoids and, more specifically, flavonols. This review summarizes the beneficial pharmaceutical effects of quercetin, such as its anti-cancer, anti-inflammatory, and antimicrobial properties, which are some of the quercetin effects described in this review. Nevertheless, quercetin shows poor bioavailability and low solubility. For this reason, its encapsulation in macromolecules increases its bioavailability and therefore pharmaceutical efficiency. In this review, a brief description of the different forms of encapsulation of quercetin are described, and new ones are proposed. The beneficial effects of applying new pharmaceutical forms of nanotechnology are outlined.

天然产物作为潜在药物先导的研究引起了极大的研究兴趣。槲皮素就是其中一种天然产物。它属于类黄酮家族，更具体地说，属于黄酮醇。本综述总结了槲皮素的有益的药物作用，如抗癌、抗炎和抗菌特性，这些都是本综述中描述的槲皮素的一些作用。然而，槲皮素的生物利用度差，溶解度低。因此，将其包裹在大分子中可以提高其生物利用度和药物效率。在本综述中，简要描述了槲皮素的不同包封形式，并提出了新的包封形式。概述了应用纳米技术新药物形式的有益效果。