Graduate School of Science and Technology, Keio University, Yokohama 223-8522, Japan.
Department of Information and Computer Science, Keio University, Yokohama 223-8522, Japan.
Sensors (Basel). 2023 Dec 8;23(24):9698. doi: 10.3390/s23249698.
Fetal heart rate (FHR) monitoring, typically using Doppler ultrasound (DUS) signals, is an important technique for assessing fetal health. In this work, we develop a robust DUS-based FHR estimation approach complemented by DUS signal quality assessment (SQA) based on unsupervised representation learning in response to the drawbacks of previous DUS-based FHR estimation and DUS SQA methods. We improve the existing FHR estimation algorithm based on the autocorrelation function (ACF), which is the most widely used method for estimating FHR from DUS signals. Short-time Fourier transform (STFT) serves as a signal pre-processing technique that allows the extraction of both temporal and spectral information. In addition, we utilize double ACF calculations, employing the first one to determine an appropriate window size and the second one to estimate the FHR within changing windows. This approach enhances the robustness and adaptability of the algorithm. Furthermore, we tackle the challenge of low-quality signals impacting FHR estimation by introducing a DUS SQA method based on unsupervised representation learning. We employ a variational autoencoder (VAE) to train representations of pre-processed fetal DUS data and aggregate them into a signal quality index (SQI) using a self-organizing map (SOM). By incorporating the SQI and Kalman filter (KF), we refine the estimated FHRs, minimizing errors in the estimation process. Experimental results demonstrate that our proposed approach outperforms conventional methods in terms of accuracy and robustness.
胎儿心率(FHR)监测通常使用多普勒超声(DUS)信号,是评估胎儿健康的重要技术。在这项工作中,我们开发了一种稳健的基于 DUS 的 FHR 估计方法,并结合基于无监督表示学习的 DUS 信号质量评估(SQA),以应对以前基于 DUS 的 FHR 估计和 DUS SQA 方法的缺点。我们改进了基于自相关函数(ACF)的现有 FHR 估计算法,该算法是从 DUS 信号中估计 FHR 最广泛使用的方法。短时傅里叶变换(STFT)作为一种信号预处理技术,允许提取时间和频谱信息。此外,我们利用双 ACF 计算,第一个用于确定适当的窗口大小,第二个用于在变化的窗口内估计 FHR。这种方法增强了算法的鲁棒性和适应性。此外,我们通过引入基于无监督表示学习的 DUS SQA 方法来解决低质量信号对 FHR 估计的影响。我们使用变分自动编码器(VAE)训练预处理的胎儿 DUS 数据的表示,并使用自组织映射(SOM)将它们聚合为信号质量指数(SQI)。通过结合 SQI 和卡尔曼滤波器(KF),我们可以细化估计的 FHR,最小化估计过程中的误差。实验结果表明,我们提出的方法在准确性和鲁棒性方面优于传统方法。