Barbosa Amanda D, Egan Siobhon, Feng Yaoyu, Xiao Lihua, Ryan Una
Harry Butler Institute, Vector- and Water-Borne Pathogen Research Group, Murdoch University, Murdoch, Western Australia 6150, Australia.
CAPES Foundation, Ministry of Education of Brazil, Brasilia, DF 70040-020, Brazil.
Curr Res Parasitol Vector Borne Dis. 2023 Nov 23;4:100155. doi: 10.1016/j.crpvbd.2023.100155. eCollection 2023.
Bats are known to harbour various pathogens and are increasingly recognised as potential reservoirs for zoonotic diseases. This paper reviews the genetic diversity and zoonotic potential of and in bats. The risk of zoonotic transmission of from bats to humans appears low, with bat-specific genotypes accounting for 91.5% of positive samples genotyped from bats worldwide, and and accounting for 3.4% each of typed positives, respectively. To date, there have only been sporadic detections of in bats, with no genetic characterisation of the parasite to species or assemblage level. Therefore, the role bats play as reservoirs of zoonotic spp. is unknown. To mitigate potential risks of zoonotic transmission and their public health implications, comprehensive research on and in bats is imperative. Future studies should encompass additional locations across the globe and a broader spectrum of bat species, with a focus on those adapted to urban environments.
已知蝙蝠携带多种病原体，并且越来越被认为是人畜共患病的潜在宿主。本文综述了蝙蝠体内[具体病原体名称1]和[具体病原体名称2]的遗传多样性及人畜共患病潜力。蝙蝠将[具体病原体名称1]传播给人类的人畜共患病传播风险似乎较低，全球蝙蝠阳性样本基因分型中，蝙蝠特异性[具体病原体名称1]基因型占91.5%，[具体病原体名称3]和[具体病原体名称4]分别占分型阳性的3.4%。迄今为止，仅在蝙蝠中偶尔检测到[具体病原体名称2]，尚未对该寄生虫进行物种或组合水平的基因特征分析。因此，蝙蝠作为人畜共患[具体病原体名称2]物种宿主所起的作用尚不清楚。为降低人畜共患病传播的潜在风险及其对公共卫生的影响，对蝙蝠体内[具体病原体名称1]和[具体病原体名称2]进行全面研究势在必行。未来的研究应涵盖全球更多地点以及更广泛的蝙蝠物种，尤其关注那些适应城市环境的蝙蝠。
