Liu Sirui, Song Lin, Dai Weishu, Liu Mengdie, Zhang Huijing, Zhang Xueyan, Li Hongyu, Liu Xiu, Lv Yan, Hu Ying
Beijing Institute of Dental Research, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Department of Periodontology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Front Bioeng Biotechnol. 2023 Feb 27;11:1094059. doi: 10.3389/fbioe.2023.1094059. eCollection 2023.
We investigated the current state and trends in the area during the previous 10 years using bibliometric approaches to evaluate the global scientific output of research on electroactive materials and spinal cord injury. Studies on spinal cord injury in electroactive materials that were published between 2012 and 2022 were located using the Web of science (WOS) datebase. The software programs bibliometrix R-package and CiteSpace were used to do quantitative analyses of annual publications, nation, author, institution, journal source, co-cited references, and keywords. The studies were categorized by the research's main points using a qualitative analysis, and publications having more than 10 citations each year. In the final analysis, 1,330 relevant papers or reviews were included. There is an increased tendency in both the average annual citation rate and the number of publications in the discipline. The United States and the University of Toronto are the countries and institutions that have contributed the most to this discipline, respectively. The majority of authors are from the China and United States. Zhang Y is the author with the most published articles and holds the top position in the cited author h-index species. The journal with the highest number of published articles is "Disability and rehabilitation"; the journal is divided into four main areas including physics, materials, chemistry, molecular, and biology. The keyword analysis revealed a shift in research hotspots from schwann cell, fracture, and urinary disorders to carbon-based materials, functional recovery, and surgery. Analysis of qualitative data revealed that the role and mechanism of injectable conductive hydrogels in spinal cord healing after damage is a hot topic of current study, with the mechanism primarily focusing on the inhibition of oxidative stress (Nrf2) and apoptosis (Casepase 3). Our bibliometric analysis indicates that research on electroactive materials for spinal cord injury remains an active field of study. Moreover, contemporary research is concentrated on carbon-based materials, functional rehabilitation, and surgery.
我们使用文献计量学方法,对过去10年该领域的现状和趋势进行了调查,以评估电活性材料与脊髓损伤研究的全球科学产出。利用科学网(WOS)数据库检索了2012年至2022年间发表的关于电活性材料中脊髓损伤的研究。使用文献计量学R包和CiteSpace软件程序,对年度出版物、国家、作者、机构、期刊来源、共被引参考文献和关键词进行了定量分析。通过定性分析,根据研究要点对这些研究进行了分类,并筛选出每年被引次数超过10次的出版物。最终分析纳入了1330篇相关论文或综述。该学科的年均被引率和出版物数量均呈上升趋势。美国和多伦多大学分别是对该学科贡献最大的国家和机构。大多数作者来自中国和美国。张Y是发表文章最多的作者,在所引用作者的h指数排名中位居榜首。发表文章数量最多的期刊是《残疾与康复》;该期刊分为物理、材料、化学、分子和生物学四个主要领域。关键词分析表明,研究热点已从雪旺细胞、骨折和泌尿系统疾病,转向碳基材料、功能恢复和手术。定性数据分析显示,可注射导电水凝胶在脊髓损伤后愈合中的作用和机制是当前研究的热点话题,其机制主要集中在抑制氧化应激(Nrf2)和细胞凋亡(半胱天冬酶3)。我们的文献计量分析表明,用于脊髓损伤的电活性材料研究仍然是一个活跃的研究领域。此外,当代研究集中在碳基材料、功能康复和手术方面。