Department of Spine Surgery, Ningbo No. 2 Hospital, Ningbo, Zhejiang, China.
Department of Orthopedics, Ningbo No. 2 Hospital, Ningbo, Zhejiang, China.
Medicine (Baltimore). 2024 Sep 13;103(37):e39641. doi: 10.1097/MD.0000000000039641.
Little is known about the relationship between sleep duration and quality and the risk of arthritis in the older adult population of China. The participants were a prospective cohort of adults aged 65 years and over who had not had arthritis at baseline and had participated in follow-up surveys from 2011 to 2018 in the Chinese Longitudinal Health and Longevity Survey (CLHLS). A Cox proportional-hazards regression model was established. The dose-response relationship between sleep duration and the incidence of arthritis was analyzed. The results of a Cox proportional-risk regression model revealed that sleep duration and quality were associated with the risk of arthritis in the participants. Specifically, compared with participants with good sleep quality, those with poor sleep quality had a 38% higher risk of developing arthritis (hazard ratio [HR] = 1.38, 95% confidence interval [CI] = 1.09-1.74), and compared with participants with a sleep duration of 5 to 10 hours, those with a sleep duration shorter than 5 hours had a higher risk of developing arthritis (HR = 1.56, 95% CI = 1.27-1.91). Moreover, the results of a restricted cubic spline Cox proportional-hazards regression model showed that there was an approximately non-linear dose-response relationship between sleep duration and the incidence rate of arthritis (P nonlinear < .0001). Participants with poor sleep quality and a sleep duration shorter than 5 hours had a higher risk of developing arthritis than those with better sleep quality and a longer sleep duration.
关于中国 65 岁及以上老年人的睡眠时长和质量与关节炎风险之间的关系知之甚少。本研究参与者为前瞻性队列研究，均为基线时无关节炎且于 2011 年至 2018 年参加中国健康长寿纵向研究（CLHLS）随访调查的成年人。采用 Cox 比例风险回归模型建立。分析了睡眠时长与关节炎发病风险之间的剂量-反应关系。Cox 比例风险回归模型的结果显示，睡眠时长和质量与参与者的关节炎风险相关。具体而言，与睡眠质量良好的参与者相比，睡眠质量差的参与者患关节炎的风险增加 38%（风险比[HR] = 1.38，95%置信区间[CI] = 1.09-1.74）；与睡眠时间为 5-10 小时的参与者相比，睡眠时间少于 5 小时的参与者患关节炎的风险更高（HR = 1.56，95%CI = 1.27-1.91）。此外，受限立方样条 Cox 比例风险回归模型的结果表明，睡眠时长与关节炎发病率之间存在近似非线性的剂量-反应关系（P 非线性<0.0001）。睡眠质量差且睡眠时间短于 5 小时的参与者患关节炎的风险高于睡眠质量较好且睡眠时间较长的参与者。
