School of dental sciences, Universiti Sains Malaysia, Health Campus, Kelantan, Malaysia.
Qilu Medical University, Zibo, China.
Curr Pharm Biotechnol. 2024;25(14):1767-1777. doi: 10.2174/0113892010276692231220103636.
Primarily sourced from Asteraceae family herbs such as the Dandelion, Taraxasterol is a pentacyclic triterpenoid lauded for its extensive biological functionalities. Its therapeutic potency is demonstrated in various disease models, encompassing enteritis, arthritis, acute hepatic injury, and pneumonia. Scientific literature underscores its anti-inflammatory, antioxidant, and antineoplastic attributes. The primary aim of this study is to thoroughly explore the diseasemodulating mechanisms and effects of taraxasterol. We endeavor to provide an exhaustive review of the experimental subjects, intervention components, distinct action modalities, contributing factors, and protein pathway expressions associated with taraxasterol, systematically represented via diagrams and tables. Such a schematic representation encourages a continued academic dialogue concerning taraxasterol's pharmacological characteristics. This review is envisioned as a practical guide for the selection of experimental subjects and methodologies in prospective research. It is intended to further illuminate taraxasterol's pharmacodynamics, thereby offering theoretical and empirical justification for its clinical application.
蒲公英等菊科草本植物是 Taraxasterol 的主要来源，这种五环三萜被广泛赞誉为具有多种生物学功能。它在各种疾病模型中都表现出治疗作用，包括肠炎、关节炎、急性肝损伤和肺炎。科学文献强调了它的抗炎、抗氧化和抗肿瘤特性。本研究的主要目的是深入探索 Taraxasterol 的疾病调节机制和效果。我们努力全面回顾 Taraxasterol 的实验对象、干预成分、不同作用方式、影响因素和与 Taraxasterol 相关的蛋白通路表达，并通过图表和表格进行系统呈现。这种示意图表示法鼓励就 Taraxasterol 的药理学特征进行持续的学术对话。本综述旨在为未来研究中实验对象和方法的选择提供实用指南。它旨在进一步阐明 Taraxasterol 的药效学，从而为其临床应用提供理论和经验依据。
