Wu Jianhao, Sun Jialin, Liu Meiqi, Zhang Xiaozhuang, Kong Lingyang, Ma Lengleng, Jiang Shan, Liu Xiubo, Ma Wei
School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150006, China.
School of Jiamusi, Heilongjiang University of Chinese Medicine, Jiamusi 154007, China.
Pharmaceuticals (Basel). 2024 Aug 23;17(9):1113. doi: 10.3390/ph17091113.
, as a traditional Chinese medicine, is the name of the genus in the family. Documented in the Tang Herbal Medicine (Tang Dynasty, AD 657-659), its medicinal properties cover a wide range of applications such as acute mastitis, lung abscess, conjunctival congestion, sore throat, damp-heat jaundice, and vision improvement. In the Chinese Pharmacopoeia (Edition 2020), more than 40 kinds of China-patented drugs containing were recorded. This review explores the evolving scientific understanding of , covering facets of ethnopharmacology, botany, phytochemistry, pharmacology, artificial cultivation, and quality control. In particular, the chemical constituents and pharmacological research are reviewed. has been certified as a traditional medicine plant, and its flavonoids, phenolic acids, and terpenoids have been identified and separated, which include Chicoric acid, taraxasterol, Taraxasteryl acetate, Chlorogenic acid, isorhamnetin, and luteolin; they are responsible for anti-inflammatory, antioxidant, antibacterial, anti-tumor, and anti-cancer activities. These findings validate the traditional uses of and lay the groundwork for further scientific exploration. The sources used in this study include Web of Science, Pubmed, the CNKI site, classic monographs, the Chinese Pharmacopoeia, the Chinese Medicine Dictionary, and doctoral and master's theses.
作为一种传统中药,是科属的名称。《唐本草》(公元657 - 659年,唐朝)中有记载,其药用特性涵盖广泛应用,如急性乳腺炎、肺脓肿、结膜充血、喉咙痛、湿热黄疸和改善视力等。《中国药典》(2020年版)记录了40多种含有的中国专利药物。本综述探讨了对的科学认识的演变,涵盖民族药理学、植物学、植物化学、药理学、人工栽培和质量控制等方面。特别对其化学成分和药理学研究进行了综述。已被认证为传统药用植物,其黄酮类、酚酸类和萜类化合物已被鉴定和分离,其中包括菊苣酸、蒲公英甾醇、乙酸蒲公英甾醇酯、绿原酸、异鼠李素和木犀草素;它们具有抗炎、抗氧化、抗菌、抗肿瘤和抗癌活性。这些发现证实了的传统用途,并为进一步的科学探索奠定了基础。本研究使用的资料来源包括科学网、PubMed、中国知网网站、经典专著、《中国药典》、《中药大词典》以及博士和硕士论文。