Camacho T C, Kaplan G A, Cohen R D
J Chronic Dis. 1987;40(3):229-36. doi: 10.1016/0021-9681(87)90158-5.
The association between level of alcohol consumption and 15-year mortality, focusing particularly on the possible protective effect of light drinking compared to abstention, was studied in a representative population sample of 6928 residents of Alameda County, California. Because abstainers differ from light, moderate and heavy drinkers on a number of demographic, physical, and psychosocial characteristics, the role of these as confounders of the alcohol/mortality association was examined. Using multiple logistic models, the mortality experience of abstainers, moderate drinkers, heavy drinkers and very heavy drinkers was compared with that of light drinkers. Among men only, very heavy drinkers were at significantly greater risk of death from all causes than were light drinkers (OR = 2.5, p less than 0.01). Neither abstainers nor other drinkers were at significantly higher risk of death from ischemic heart disease than were light drinkers. This pattern of results persisted with adjustment for 11 covariates of alcohol consumption in addition to age.
在加利福尼亚州阿拉米达县6928名居民的代表性人群样本中,研究了酒精消费水平与15年死亡率之间的关联,尤其关注与戒酒相比,轻度饮酒可能具有的保护作用。由于戒酒者在一些人口统计学、身体和心理社会特征方面与轻度、中度和重度饮酒者不同,因此研究了这些因素作为酒精/死亡率关联混杂因素的作用。使用多重逻辑模型,将戒酒者、中度饮酒者、重度饮酒者和极重度饮酒者的死亡经历与轻度饮酒者进行了比较。仅在男性中,极重度饮酒者因各种原因死亡的风险显著高于轻度饮酒者(比值比=2.5,p<0.01)。戒酒者和其他饮酒者因缺血性心脏病死亡的风险均未显著高于轻度饮酒者。除年龄外,对11个酒精消费协变量进行调整后,这种结果模式依然存在。