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饮酒与死亡率。I. 饮酒群体的特征。

Alcohol consumption and mortality. I. Characteristics of drinking groups.

作者信息

Fillmore K M, Golding J M, Graves K L, Kniep S, Leino E V, Romelsjö A, Shoemaker C, Ager C R, Allebeck P, Ferrer H P

机构信息

Department of Social and Behavioral Sciences, University of California, San Francisco 94143-0646, USA.

出版信息

Addiction. 1998 Feb;93(2):183-203. doi: 10.1046/j.1360-0443.1998.9321834.x.

Abstract

AIMS

This is the first of a set of three papers evaluating drinking status and mortality risk. Analyses of multiple studies describe associations of drinking patterns with characteristics hypothesized to confound the relationships between drinking status and mortality. Characteristics which both significantly differentiate drinking groups and are consistent across studies would suggest that mortality studies not controlling for them may be compromised.

DESIGN AND PARTICIPANTS

Associations are evaluated from the raw data of 10 general population studies which contained mortality data. Long-term abstainers are compared to former drinkers, long-term abstainers and former drinkers are compared to light drinkers (by quantity, frequency and volume in separate analyses) and moderate to heavy drinkers are compared to light drinkers. Tetrachoric correlation coefficients assess statistical significance; meta-analysis determines if associations are homogeneous across studies.

MEASUREMENTS

Measures of alcohol consumption are quantity, frequency and volume; long-term abstainers are differentiated from former drinkers. Multiple measures of health, social position, social integration and mental health characteristics are evaluated.

FINDINGS

Across studies, adult male former drinkers are consistently more likely to be heavier smokers, depressed, unemployed, lower SES and to have used marijuana than long-term abstainers. Adult female former drinkers are consistently more likely to be heavier smokers, in poorer health, not religious, and unmarried than long-term abstainers. Both types of abstainers tend to be of lower SES than light drinkers and report poorer health (not consistent). Female abstainers are more likely to be of normal or overweight than light drinkers.

CONCLUSIONS

Characteristics of two groups of abstainers, other than their non-use of alcohol, may confound the associations found between drinking and mortality risk.

摘要

目的

这是一组三篇论文中的第一篇,旨在评估饮酒状况与死亡风险。多项研究分析描述了饮酒模式与一些特征之间的关联,这些特征被认为会混淆饮酒状况与死亡率之间的关系。那些既能显著区分饮酒群体,又在各项研究中保持一致的特征,表明未对其进行控制的死亡率研究可能存在缺陷。

设计与参与者

从10项包含死亡率数据的一般人群研究的原始数据中评估关联。将长期戒酒者与既往饮酒者进行比较,将长期戒酒者和既往饮酒者与轻度饮酒者进行比较(分别按饮酒量、饮酒频率和饮酒总量进行分析),并将中度至重度饮酒者与轻度饮酒者进行比较。四分相关系数评估统计学意义;荟萃分析确定各项研究之间的关联是否具有同质性。

测量指标

酒精摄入量的测量指标为饮酒量、饮酒频率和饮酒总量;区分长期戒酒者和既往饮酒者。评估多项健康、社会地位、社会融合和心理健康特征指标。

研究结果

在各项研究中,成年男性既往饮酒者相比于长期戒酒者,持续表现出更有可能是重度吸烟者、抑郁、失业、社会经济地位较低且使用过大麻。成年女性既往饮酒者相比于长期戒酒者,持续表现出更有可能是重度吸烟者、健康状况较差、无宗教信仰且未婚。两类戒酒者的社会经济地位往往都低于轻度饮酒者,且报告的健康状况较差(不一致)。女性戒酒者相比于轻度饮酒者更有可能体重正常或超重。

结论

两组戒酒者除了不饮酒之外的其他特征,可能会混淆饮酒与死亡风险之间的关联。

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