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酷似转移性疾病的多灶性肝脂肪结节:一例报告。

Multifocal fatty liver nodules mimicking a metastatic disease: A case report.

作者信息

Duong Huy Quang, Kajiura Shinya, Truong Tien Dinh, Ngo Minh Tuan, Nguyen Khai Xuan, Pham Hung Khanh, Ta Thang Ba, Nguyen Dung Tien, Hayashi Ryuji

机构信息

Department of Gastroenterology, 103 Military Hospital, Vietnam Military Medical University, Hanoi, Vietnam.

Department of Clinical Oncology, Toyama University Hospital, Toyama, Japan.

出版信息

Radiol Case Rep. 2023 Dec 15;19(3):850-854. doi: 10.1016/j.radcr.2023.11.040. eCollection 2024 Mar.

DOI:10.1016/j.radcr.2023.11.040
PMID:38188964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10770493/
Abstract

Multifocal fatty liver nodules can present a diagnostic challenge due to their resemblance to metastatic liver disease. This case report illustrates the complexity of such scenarios through the presentation of a middle-aged male patient. Despite the common nature of fatty liver disease, characterized by hepatocyte fat accumulation leading to diffuse and uniform liver lesions, rare instances exhibit heterogeneous appearances. The case underlines the potential confusion arising from imaging modalities when multiple small nodules disperse throughout the liver, mimicking multifocal tumors or metastases. The report emphasizes the critical role of comprehensive diagnostic procedures in preventing misdiagnosis and unwarranted interventions. Effective management hinges on multidisciplinary collaboration among specialists, ensuring accurate differentiation and appropriate treatment. This study serves as a reminder of the intricacies involved in interpreting multifocal fatty liver nodules that may masquerade as metastatic disease, highlighting the need for precision in clinical practice.

摘要

多灶性脂肪肝结节因其与肝转移瘤相似,可能带来诊断挑战。本病例报告通过一名中年男性患者的病例展示了此类情况的复杂性。尽管脂肪肝疾病较为常见,其特征是肝细胞脂肪堆积导致肝脏弥漫性和均匀性病变,但罕见情况下会呈现异质性表现。该病例突显了在多个小结节散布于肝脏,酷似多灶性肿瘤或转移瘤时,成像方式可能引发的混淆。报告强调了全面诊断程序在防止误诊和不必要干预方面的关键作用。有效管理取决于专家之间的多学科协作,以确保准确鉴别和恰当治疗。本研究提醒人们注意解读可能伪装成转移性疾病的多灶性脂肪肝结节所涉及的复杂性,凸显了临床实践中精准诊断的必要性。

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本文引用的文献

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Non-Invasive Imaging Methods to Evaluate Non-Alcoholic Fatty Liver Disease with Fat Quantification: A Review.用于评估非酒精性脂肪性肝病并进行脂肪定量的非侵入性成像方法:综述
Diagnostics (Basel). 2023 May 25;13(11):1852. doi: 10.3390/diagnostics13111852.
2
Multifocal nodular lesions in fatty liver mimicking neoplastic disease: a case report.脂肪肝中酷似肿瘤性疾病的多灶性结节性病变:一例报告
Future Sci OA. 2023 Mar 28;9(4):FSO848. doi: 10.2144/fsoa-2022-0084. eCollection 2023 Apr.
3
Global incidence and prevalence of nonalcoholic fatty liver disease.
全球非酒精性脂肪性肝病的发病率和患病率。
Clin Mol Hepatol. 2023 Feb;29(Suppl):S32-S42. doi: 10.3350/cmh.2022.0365. Epub 2022 Dec 14.
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Fat-Containing Liver Lesions on Imaging: Detection and Differential Diagnosis.影像学表现的含脂肝脏病变:检测与鉴别诊断。
AJR Am J Roentgenol. 2018 Jan;210(1):68-77. doi: 10.2214/AJR.17.18136. Epub 2017 Oct 24.
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Can J Gastroenterol Hepatol. 2016;2016:4930987. doi: 10.1155/2016/4930987. Epub 2016 Apr 19.
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Pathogenesis and Prevention of Hepatic Steatosis.肝脂肪变性的发病机制与预防
Gastroenterol Hepatol (N Y). 2015 Mar;11(3):167-75.
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Multifocal Nodular Fatty Infiltration of the Liver: A Case Report of a Challenging Diagnostic Problem.肝脏多灶性结节性脂肪浸润:一个具有挑战性诊断问题的病例报告
Am J Case Rep. 2016 Mar 27;17:196-202. doi: 10.12659/ajcr.897283.
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The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association.非酒精性脂肪性肝病的诊断与管理:美国肝病研究协会、美国胃肠病学会和美国胃肠病协会实践指南
Hepatology. 2012 Jun;55(6):2005-23. doi: 10.1002/hep.25762.
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Fatty liver deposition and sparing: a pictorial review.脂肪肝沉积与肝岛:影像学综述
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Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: a meta-analysis.超声检查诊断脂肪肝的准确性和可靠性:一项荟萃分析。
Hepatology. 2011 Sep 2;54(3):1082-1090. doi: 10.1002/hep.24452.