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前白蛋白:其与淀粉样蛋白的关联

Prealbumin: its association with amyloid.

作者信息

Cornwell G G, Sletten K, Olofsson B O, Johansson B, Westermark P

出版信息

J Clin Pathol. 1987 Feb;40(2):226-31. doi: 10.1136/jcp.40.2.226.

Abstract

In recent years prealbumin has been shown to be a major component of two forms of systemic amyloid, senile systemic amyloid (SSA), and familial amyloidotic polyneuropathy (FAP). Despite the fact that the amyloid fibril proteins associated with these two forms of amyloid, designated ASc1 and AF, respectively, share many similarities the clinical features of the two diseases are remarkably different. To understand better this paradox the clinical, histochemical, immunological and biochemical features of SSA and FAP were reviewed.

摘要

近年来,前白蛋白已被证明是两种系统性淀粉样变性的主要成分,即老年系统性淀粉样变性(SSA)和家族性淀粉样多神经病(FAP)。尽管与这两种淀粉样变性相关的淀粉样纤维蛋白(分别命名为ASc1和AF)有许多相似之处,但这两种疾病的临床特征却显著不同。为了更好地理解这一矛盾现象,我们回顾了SSA和FAP的临床、组织化学、免疫学和生物化学特征。

相似文献

1
Prealbumin: its association with amyloid.前白蛋白:其与淀粉样蛋白的关联
J Clin Pathol. 1987 Feb;40(2):226-31. doi: 10.1136/jcp.40.2.226.

本文引用的文献

2
Senile cardiac amyloid is related to prealbumin.老年心脏淀粉样变与前白蛋白有关。
Scand J Immunol. 1980;12(6):503-6. doi: 10.1111/j.1365-3083.1980.tb00098.x.
6
Polymorphism of human plasma thyroxine binding prealbumin.人血浆甲状腺素结合前白蛋白的多态性
Biochem Biophys Res Commun. 1983 Jul 29;114(2):657-62. doi: 10.1016/0006-291x(83)90831-8.

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