• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

非特异性痴呆、皮质盲和嗜刚果红血管病。一份临床病理报告。

Nonspecific dementia, cortical blindness, and Congophilic angiopathy. A clinicopathological report.

作者信息

Nadeau S E, Bebin J, Smith E

出版信息

J Neurol. 1987 Jan;234(1):14-8. doi: 10.1007/BF00314002.

DOI:10.1007/BF00314002
PMID:3819782
Abstract

Postmortem examination of an elderly male with cortical blindness and features of both cortical and subcortical dementia revealed extensive neuronal dropout most marked in the occipital cortex, moderate gliosis, rare neuritic plaques, no neurofibrillary tangles, and extensive Congophilic angiopathy. The unprecedented association of Congophilic angiopathy with nonspecific dementia provides further support for the concept that Congophilic angiopathy is usually a nonspecific manifestation of neuronal degeneration and of little clinical significance except when it results in intracerebral hemorrhage.

摘要

对一名患有皮质盲以及皮质和皮质下痴呆特征的老年男性进行的尸检显示,广泛的神经元脱失在枕叶皮质最为明显,有中度胶质细胞增生,罕见神经炎性斑块,无神经原纤维缠结,以及广泛的嗜刚果红血管病。嗜刚果红血管病与非特异性痴呆前所未有的关联进一步支持了这样一种观念,即嗜刚果红血管病通常是神经元变性的非特异性表现,除了导致脑出血外临床意义不大。

相似文献

1
Nonspecific dementia, cortical blindness, and Congophilic angiopathy. A clinicopathological report.非特异性痴呆、皮质盲和嗜刚果红血管病。一份临床病理报告。
J Neurol. 1987 Jan;234(1):14-8. doi: 10.1007/BF00314002.
2
Congophilic angiopathy in the pathogenesis of Alzheimer's degeneration.嗜刚果红血管病在阿尔茨海默病变性发病机制中的作用
Ann Pathol. 1981;1(2):120-9.
3
Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles.荷兰型遗传性脑出血伴淀粉样变性中的痴呆与脑淀粉样血管病相关,但与斑块和神经原纤维缠结无关。
Ann Neurol. 2001 Dec;50(6):765-72. doi: 10.1002/ana.10040.
4
Congophilic angiopathy with cerebrospinal symptoms.伴有脑脊液症状的嗜刚果红血管病
Eur Arch Psychiatry Neurol Sci. 1987;236(5):281-7. doi: 10.1007/BF00380953.
5
Microglia in diffuse plaques in hereditary cerebral hemorrhage with amyloidosis (Dutch). An immunohistochemical study.遗传性淀粉样变性脑出血(荷兰型)弥漫性斑块中的小胶质细胞。一项免疫组织化学研究。
J Neuropathol Exp Neurol. 1994 Sep;53(5):483-91. doi: 10.1097/00005072-199409000-00007.
6
Relationship between numbers of cortical argentophilic and congophilic senile plaques in the brains of elderly people with and without senile dementia of Alzheimer type.患有和未患有阿尔茨海默型老年痴呆症的老年人大脑中皮质嗜银性和嗜刚果红性老年斑数量之间的关系。
Gerontology. 1985;31(5):321-4. doi: 10.1159/000212716.
7
Intracerebral hemorrhage due to cerebral amyloid angiopathy. Case report.脑淀粉样血管病所致脑出血。病例报告。
J Neurosurg. 1985 Dec;63(6):965-9. doi: 10.3171/jns.1985.63.6.0965.
8
Cerebral amyloid angiopathy: incidence and complications in the aging brain. I. Cerebral hemorrhage.脑淀粉样血管病:衰老大脑中的发病率及并发症。I. 脑出血
Stroke. 1983 Nov-Dec;14(6):915-23. doi: 10.1161/01.str.14.6.915.
9
Congophilic angiopathy of the brain: a clinical and pathological report on two siblings.脑嗜刚果红血管病:两例同胞患者的临床与病理报告
J Neurol Neurosurg Psychiatry. 1982 May;45(5):396-408. doi: 10.1136/jnnp.45.5.396.
10
[Morphologic diagnosis of vascular and senile dementia (the significance of Congophilic angiopathy)].[血管性和老年性痴呆的形态学诊断(嗜刚果红血管病的意义)]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(7):35-9.

引用本文的文献

1
[The clinical syndrome of posterior cortical atrophy].[后皮质萎缩的临床综合征]
Nervenarzt. 2006 Feb;77(2):208-14. doi: 10.1007/s00115-005-1987-5.
2
Brain amyloid in normal aging and cerebral amyloid angiopathy is antigenically related to Alzheimer's disease beta-protein.正常衰老和脑淀粉样血管病中的脑淀粉样蛋白在抗原性上与阿尔茨海默病β蛋白相关。
Am J Pathol. 1987 Dec;129(3):422-8.
3
beta-amyloid protein of Alzheimer's disease is found in cerebral and spinal cord vascular malformations.阿尔茨海默病的β-淀粉样蛋白存在于脑和脊髓血管畸形中。

本文引用的文献

1
Combined amyloid vascular changes and argyrophilic plaques in the central nervous system.中枢神经系统中合并存在的淀粉样血管病变和嗜银斑。
J Neuropathol Exp Neurol. 1960 Jul;19:370-82. doi: 10.1097/00005072-196007000-00005.
2
[A particular type of senile angiopathy of the central nervous system: congophilic angiopathy, topography and frequency].[一种特殊类型的中枢神经系统老年血管病:嗜刚果红血管病,部位及发生率]
Monatsschr Psychiatr Neurol. 1954 Oct;128(4):219-56.
3
[Dementia pugilistica with anatomical findings].伴有解剖学发现的拳击性痴呆
Am J Pathol. 1988 Jul;132(1):167-72.
Virchows Arch Pathol Anat Physiol Klin Med. 1954;325(6):680-709. doi: 10.1007/BF00955101.
4
Familial dementia of adult onset with pathological findings of a 'non-specific' nature.具有“非特异性”病理表现的成年起病型家族性痴呆。
Brain. 1981 Mar;104(Pt 1):61-78. doi: 10.1093/brain/104.1.61.
5
A typical presenile dementia. Report of an anatomo-clinical case and review of the literature.一例典型的早老性痴呆。解剖临床病例报告及文献复习。
J Neurol Sci. 1981 Nov-Dec;52(2-3):245-67. doi: 10.1016/0022-510x(81)90009-5.
6
Cerebral amyloid angiopathy.脑淀粉样血管病
Hum Pathol. 1981 Jul;12(7):609-16. doi: 10.1016/s0046-8177(81)80044-5.
7
Cerebral amyloid angiopathy in the elderly.老年人的脑淀粉样血管病
J Am Geriatr Soc. 1981 Apr;29(4):151-7. doi: 10.1111/j.1532-5415.1981.tb01757.x.
8
Amyloid and senile plaques and cerebral blood vessels. A semi-quantitative investigation of a possible relationship.淀粉样蛋白、老年斑与脑血管。对一种可能关系的半定量研究。
J Neurol Sci. 1982 Nov-Dec;57(1):89-103. doi: 10.1016/0022-510x(82)90113-7.
9
Familial cerebral amyloid angiopathy presenting as recurrent cerebral haemorrhage.表现为复发性脑出血的家族性脑淀粉样血管病。
J Neurol Sci. 1982 Aug;55(2):121-35. doi: 10.1016/0022-510x(82)90094-6.
10
Congophilic angiopathy of the brain: a clinical and pathological report on two siblings.脑嗜刚果红血管病:两例同胞患者的临床与病理报告
J Neurol Neurosurg Psychiatry. 1982 May;45(5):396-408. doi: 10.1136/jnnp.45.5.396.