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在前颈部鲍恩病广泛皮肤手术后的两阶段重建中使用真皮再生模板——病例报告

Use of a Dermal Regeneration Template in a two-stage reconstruction after extensive skin surgery for Bowen's disease of the anterior neck - Case report.

作者信息

Grassi Davide, De Monti Marco, Espeli Vittoria, De Pellegrin Laura

机构信息

EOC - Mendrisio Beata Vergine Regional Hospital - Department of General Surgery, Switzerland.

EOC - Mendrisio Beata Vergine Regional Hospital - Department of General Surgery, Switzerland.

出版信息

Int J Surg Case Rep. 2024 Feb;115:109208. doi: 10.1016/j.ijscr.2023.109208. Epub 2023 Dec 30.

DOI:10.1016/j.ijscr.2023.109208
PMID:38199019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10824778/
Abstract

INTRODUCTION

Dermal Regeneration Templates may be used in the reconstruction of large skin defects after cutaneous malignancy excisions. Bowen's disease (BD; squamous cell carcinoma in situ) is a common and persistent condition that can be related to chronic sun damage, and consequently, is usually located on the head and neck area or on the lower limbs. Literature does not provide clear guidelines on the treatment of BD, limiting itself to describing a wide range of different methods that can be used, including surgery, laser therapy or topical options. However, large lesions tend to scar in the post-operative setting and hence are difficult to treat surgically.

PRESENTATION OF CASE

In this paper the authors present a case of a male in his 60s, ASA III score, who presented with a history of histopathologically-confirmed squamocellular carcinoma in the neck and supraclavicular region. Due to recurrent carcinomas the patient was treated with an extensive skin excision and a successful reconstruction using a Dermal Regeneration Template. The work has been reported in line with the SCARE criteria.

DISCUSSION

The main surgical problem caused by BD is reaching complete oncological resection and, consequently, the need for extensive skin excisions.

CONCLUSION

The use of the skin substitute resulted in a satisfactory functional and aesthetic result, with total clearance and no recurrence observed after 16 months.

摘要

引言

真皮再生模板可用于皮肤恶性肿瘤切除术后大面积皮肤缺损的重建。鲍恩病(BD;原位鳞状细胞癌)是一种常见且持续存在的疾病,可能与慢性阳光损伤有关,因此通常位于头颈部或下肢。文献中没有提供关于BD治疗的明确指南,仅局限于描述一系列可使用的不同方法,包括手术、激光治疗或局部治疗方案。然而,大的病变在术后往往会留下疤痕,因此手术治疗困难。

病例介绍

本文作者介绍了一例60多岁、美国麻醉医师协会(ASA)Ⅲ级评分的男性患者,其颈部和锁骨上区域有组织病理学确诊的鳞状细胞癌病史。由于复发性癌,患者接受了广泛的皮肤切除,并使用真皮再生模板成功进行了重建。该病例报告符合SCARE标准。

讨论

BD引起的主要手术问题是实现彻底的肿瘤切除,因此需要广泛的皮肤切除。

结论

使用皮肤替代物取得了令人满意的功能和美学效果,实现了完全清除,16个月后未观察到复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/20c595aa51b7/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/159251439b91/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/996ca09c8e4b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/c5034ac2bf00/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/0bdd0b536dea/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/b2005440271b/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/fd8ee2caff30/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/d06705941054/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/20c595aa51b7/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/159251439b91/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/996ca09c8e4b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/c5034ac2bf00/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/0bdd0b536dea/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/b2005440271b/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/fd8ee2caff30/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/d06705941054/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c3/10824778/20c595aa51b7/gr8.jpg

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本文引用的文献

1
The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
2
Cutaneous Squamous Cell Carcinoma.皮肤鳞状细胞癌。
Hematol Oncol Clin North Am. 2019 Feb;33(1):1-12. doi: 10.1016/j.hoc.2018.08.001.
3
The PROCESS 2018 statement: Updating Consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) guidelines.PROCESS 2018 声明:更新外科手术病例系列报告的共识首选报告规范(PROCESS)指南。
Int J Surg. 2018 Dec;60:279-282. doi: 10.1016/j.ijsu.2018.10.031. Epub 2018 Oct 22.
4
Skin Cancer Epidemics in the Elderly as An Emerging Issue in Geriatric Oncology.老年皮肤癌流行:老年肿瘤学中的一个新问题
Aging Dis. 2017 Oct 1;8(5):643-661. doi: 10.14336/AD.2017.0503. eCollection 2017 Oct.
5
The burden of skin disease in the United States.美国的皮肤病负担。
J Am Acad Dermatol. 2017 May;76(5):958-972.e2. doi: 10.1016/j.jaad.2016.12.043. Epub 2017 Mar 1.
6
One-Stage Reconstruction of Scalp after Full-Thickness Oncologic Defects Using a Dermal Regeneration Template (Integra).使用真皮再生模板(Integra)对头皮全层肿瘤性缺损进行一期重建。
Biomed Res Int. 2015;2015:698385. doi: 10.1155/2015/698385. Epub 2015 Nov 16.
7
Vital signs: melanoma incidence and mortality trends and projections - United States, 1982-2030.生命体征:美国1982 - 2030年黑色素瘤发病率、死亡率趋势及预测
MMWR Morb Mortal Wkly Rep. 2015 Jun 5;64(21):591-6.
8
Skin cancer: an overview of epidemiology and risk factors.皮肤癌:流行病学和危险因素概述。
Semin Oncol Nurs. 2013 Aug;29(3):160-9. doi: 10.1016/j.soncn.2013.06.002.
9
Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification--part two.皮肤鳞状细胞癌:综合临床病理分类——第二部分
J Cutan Pathol. 2006 Apr;33(4):261-79. doi: 10.1111/j.0303-6987.2006.00516.x.
10
Reconstructive surgery.整形手术
BMJ. 2006 Mar 25;332(7543):710-2. doi: 10.1136/bmj.332.7543.710.