Choi H, Snyder H M, Duckett J W
J Pediatr Surg. 1987 Feb;22(2):158-64. doi: 10.1016/s0022-3468(87)80438-4.
During the past 12 years, 62 children with urinary stones have been treated at the Children's Hospital of Philadelphia. The most common presenting symptoms were abdominal or flank pain (45%), recurrent or persistent pyuria (35%), and gross hematuria (21%). Twenty-two patients had associated congenital urologic anomalies. Infection-related struvite stones were most common and were found in 18 children, of whom 15 were found to have anatomic abnormalities. Eighteen of 28 children evaluated for a metabolic cause were found to have an abnormality, most frequently hypercalciuria. No predisposing factors could be found in 16 of the 62 patients. Forty-four (87%) children had upper urinary tract stones. Twelve of 15 bladder stones were in children with a neuropathic bladder and all were related to infection. Treatment was directed to the correction of anatomic and metabolic predisposing causes, as well as to removing the stones. Fifteen patients passed stones ranging in size from 2 to 6 mm. Forty-six surgical procedures were performed in 43 children. Pyelolithotomy and cystolithotomy were the most frequent procedures. There were three residual stones and five recurrences. Of the 29 operations for upper urinary stones reviewed, 17 might today be considered suitable for percutaneous nephrostolithotripsy or extracorporeal shockwave lithotripsy. Possible future stone management will be discussed in light of this analysis.
在过去12年中,费城儿童医院共治疗了62例患有尿路结石的儿童。最常见的首发症状是腹痛或胁腹痛(45%)、反复或持续脓尿(35%)以及肉眼血尿(21%)。22例患者伴有先天性泌尿系统异常。与感染相关的鸟粪石结石最为常见,在18名儿童中发现,其中15名存在解剖学异常。在评估代谢原因的28名儿童中,有18名发现异常,最常见的是高钙尿症。62例患者中有16例未发现诱发因素。44名(87%)儿童患有上尿路结石。15例膀胱结石中有12例发生在神经性膀胱患儿中,且均与感染有关。治疗针对解剖学和代谢性诱发原因的纠正以及结石的清除。15例患者排出了大小从2至6毫米不等的结石。43名儿童接受了46次外科手术。肾盂切开取石术和膀胱切开取石术是最常见的手术方式。有3例残留结石和5例复发。在回顾的29例上尿路结石手术中,如今有17例可能被认为适合经皮肾镜取石术或体外冲击波碎石术。将根据这一分析讨论未来可能的结石治疗方法。