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生物疗法时代的慢性鼻-鼻窦炎伴鼻息肉影像学

Imaging of chronic rhinosinusitis with nasal polyps in the era of biological therapies.

机构信息

Department of Translational Medical Sciences.

Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II.

出版信息

Curr Opin Allergy Clin Immunol. 2024 Aug 1;24(4):243-250. doi: 10.1097/ACI.0000000000000964. Epub 2024 Feb 12.

Abstract

PURPOSE OF REVIEW

Chronic rhinosinusitis (CRS) is a chronic inflammatory disorder of the sinonasal cavities classified into two major phenotypes: CRS with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP). The diagnosis of CRS is based on clinical symptoms associated with imaging and/or nasal endoscopy findings of mucosal inflammation.

RECENT FINDINGS

Recently, novel biological therapies have emerged as therapeutic options for CRSwNP. Imaging is helpful in deciding whether surgery is likely to be beneficial and in guiding surgery. It can also help demonstrate a clinical response to medical therapy. However, specific guidelines concerning the role of imaging in CRwNP are lacking.

SUMMARY

This article provides a comprehensive and critical multidisciplinary review of the role of conventional radiology, computed tomography (CT), and magnetic resonance imaging (MRI) in the diagnosis and characterization of CRSwNP. Since the complete characterization of nasal polyps on CT or MR images is very challenging, we provide a critical review of the best imaging methods and essential reporting elements used to assess nasal polyps.

摘要

目的综述

慢性鼻-鼻窦炎(CRS)是一种鼻-鼻窦腔的慢性炎症性疾病,分为两大主要表型:伴有鼻息肉的慢性鼻-鼻窦炎(CRSwNP)和不伴鼻息肉的慢性鼻-鼻窦炎(CRSsNP)。CRS 的诊断基于与影像学和/或鼻内镜下黏膜炎症表现相关的临床症状。

最新发现

最近,新型生物疗法已成为 CRSwNP 的治疗选择。影像学有助于判断手术是否可能有益,并指导手术。它还可以帮助显示对药物治疗的临床反应。然而,关于影像学在 CRSwNP 中的作用的具体指南尚缺乏。

总结

本文对传统放射学、计算机断层扫描(CT)和磁共振成像(MRI)在 CRSwNP 的诊断和特征中的作用进行了全面而批判性的综述。由于 CT 或 MRI 图像上对鼻息肉的完全特征描述极具挑战性,因此我们对评估鼻息肉的最佳影像学方法和基本报告要素进行了批判性回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48d4/11213496/340cfb19a835/coaci-24-243-g001.jpg

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