Manski Scott, Noverati Nicholas, Policarpo Tatiana, Rubin Emily, Shivashankar Raina
Division of Gastroenterology and Hepatology, Thomas Jefferson University, Philadelphia, PA, USA.
Crohns Colitis 360. 2023 Dec 9;6(1):otad077. doi: 10.1093/crocol/otad077. eCollection 2024 Jan.
Diet is thought to contribute to the development of inflammatory bowel disease (IBD) and may act as a mediator of inflammation in patients with IBD. Patients commonly associate their diet with symptoms and inquire about dietary modifications to manage their IBD. Without clinical guidelines and well-established nutritional data, healthcare providers managing patients with IBD may find it difficult to provide recommendations. Strong evidence for enteral nutrition, particularly in the pediatric population, has been established in Crohn's disease (CD) as a therapeutic option. Enteral nutrition may also serve as an adjunct to an exclusion diet. Recent studies such as the randomized trial comparing the Specific Carbohydrate Diet to a Mediterranean Diet in CD patients provide additional insights in forming dietary plans. A low-fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet in quiescent IBD and an anti-inflammatory diet have also been explored as adjunctive therapies. In this review, we discuss the latest evidence for the role of diet in IBD both as a therapeutic modality and as an opportunity to provide patient-centered care.
饮食被认为与炎症性肠病(IBD)的发生有关,并且可能在IBD患者中充当炎症的介质。患者通常将他们的饮食与症状联系起来,并询问饮食调整以管理他们的IBD。在没有临床指南和完善的营养数据的情况下,管理IBD患者的医疗保健提供者可能会发现很难提供建议。在克罗恩病(CD)中,肠内营养,特别是在儿科人群中的有力证据已被确立为一种治疗选择。肠内营养也可以作为排除饮食的辅助手段。最近的研究,如在CD患者中将特殊碳水化合物饮食与地中海饮食进行比较的随机试验,为制定饮食计划提供了更多见解。低可发酵寡糖、双糖、单糖和多元醇(FODMAP)饮食在静止期IBD中的应用以及抗炎饮食也已作为辅助治疗方法进行了探索。在这篇综述中,我们讨论了饮食在IBD中作为一种治疗方式以及作为提供以患者为中心的护理机会的最新证据。