Shafiee Nor Hamizah, Manaf Zahara Abdul, Mokhtar Norfilza M, Raja Ali Raja Affendi
Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Dietetics Programme, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Intest Res. 2021 Apr;19(2):171-185. doi: 10.5217/ir.2020.00035. Epub 2021 Feb 3.
Current treatment for inflammatory bowel disease (IBD) includes the application of anti-inflammatory agents for the induction and remission of IBD. However, prolonged use of anti-inflammatory agents can exert adverse effects on patients. Recently, formulated dietary approach in treating IBD patients is utilized to improve clinical activity scores. An alteration of gastrointestinal microbiota through dietary therapy was found to reduce IBD and is recognized as a promising therapeutic strategy for IBD. One of the recommended formulated diets is an anti-inflammatory diet (AID) that restricts the intake of carbohydrates with modified fatty acids. This diet also contains probiotics and prebiotics that can promote balanced intestinal microbiota composition. However, scientific evidences are limited to support this specific dietary regime in maintaining the remission and prevention relapse of IBD. Therefore, this review aimed to summarize available data from various studies to evaluate the AID diet effectiveness which will be useful for clinicians to manage their IBD patients by application of improved dietary therapy.
炎症性肠病（IBD）的当前治疗方法包括应用抗炎药物来诱导疾病缓解及维持缓解状态。然而，长期使用抗炎药物会对患者产生不良影响。近来，针对IBD患者采用定制化饮食方案来改善临床活动评分。通过饮食疗法改变胃肠道微生物群被发现可减轻IBD，并且被认为是一种有前景的IBD治疗策略。推荐的定制化饮食之一是抗炎饮食（AID），它限制摄入含改性脂肪酸的碳水化合物。这种饮食还含有益生菌和益生元，可促进肠道微生物群组成的平衡。然而，支持这种特定饮食方案用于维持IBD缓解及预防复发的科学证据有限。因此，本综述旨在总结来自各种研究的现有数据，以评估抗炎饮食的有效性，这将有助于临床医生通过应用改进的饮食疗法来管理他们的IBD患者。
