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马萨诸塞州的孕产妇死亡率。趋势与预防。

Maternal mortality in Massachusetts. Trends and prevention.

作者信息

Sachs B P, Brown D A, Driscoll S G, Schulman E, Acker D, Ransil B J, Jewett J F

出版信息

N Engl J Med. 1987 Mar 12;316(11):667-72. doi: 10.1056/NEJM198703123161105.

Abstract

To identify ways in which the safety of childbirth might be increased, we investigated the causes of death among the 886 women who died during pregnancy or within 90 days post partum ("maternal deaths") in Massachusetts from 1954 through 1985. The maternal mortality rate declined from 50 per 100,000 live births in the early 1950s to the current rate of 10 per 100,000 live births. Between one third and one half of the maternal deaths were considered to have been preventable. The leading causes of maternal death from 1954 through 1957 were infection, cardiac disease, pregnancy-induced hypertension, and hemorrhage. In contrast, from 1982 through 1985 the leading causes of death were trauma (suicide, homicide, and motor vehicle accidents) and pulmonary embolus. We observed a rapid increase in the frequency of death among women who received little or no antenatal care. From 1980 through 1984 the maternal mortality rate for white women was 9.6 per 100,000 live births, whereas for nonwhites it was 35 per 100,000 live births (relative risk, 2.9; 95 percent confidence limits, 2.5 and 3.2). Fifty percent of the nonwhite women who died during pregnancy or within 90 days post partum received little or no antenatal care, in contrast to only 15 percent of the white women. These data show that the leading causes of maternal death have changed markedly in Massachusetts during the past 30 years. Although the overall maternal mortality rate has declined sharply, further improvement may occur with better antenatal care and specific efforts to prevent trauma and pulmonary embolus.

摘要

为了确定可以提高分娩安全性的方法,我们调查了1954年至1985年间在马萨诸塞州怀孕或产后90天内死亡的886名妇女(“孕产妇死亡”)的死因。孕产妇死亡率从20世纪50年代初的每10万例活产50例下降到目前的每10万例活产10例。三分之一到二分之一的孕产妇死亡被认为是可以预防的。1954年至1957年孕产妇死亡的主要原因是感染、心脏病、妊娠高血压和出血。相比之下,1982年至1985年的主要死因是创伤(自杀、他杀和机动车事故)和肺栓塞。我们观察到接受很少或没有产前护理的妇女死亡频率迅速增加。1980年至1984年,白人妇女的孕产妇死亡率为每10万例活产9.6例,而非白人妇女为每10万例活产35例(相对风险为2.9;95%置信区间为2.5和3.2)。在怀孕或产后90天内死亡的非白人妇女中,50%接受很少或没有产前护理,而白人妇女中这一比例仅为15%。这些数据表明,在过去30年里,马萨诸塞州孕产妇死亡的主要原因发生了显著变化。尽管总体孕产妇死亡率大幅下降,但通过更好的产前护理以及预防创伤和肺栓塞的具体措施,可能会进一步改善。

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