Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Clinton Health Access Initiative, New Delhi, India.
Front Immunol. 2024 Jan 3;14:1241313. doi: 10.3389/fimmu.2023.1241313. eCollection 2023.
This review analyzed the magnitude of the COVID-19 pandemic globally and in India and the measures to counter its effect using natural and innate immune booster molecules. The study focuses on two phases: the first focuses on the magnitude, and the second on the effect of antioxidants (natural compounds) on SARS-CoV-2.
The magnitude of the prevalence, mortality, and comorbidities was acquired from the World Health Organization (WHO) report, media, a report from the Ministry of Health and Family Welfare (MoHFW), newspapers, and the National Centre of Disease Control (NCDC). Research articles from PubMed as well as other sites/journals and databases were accessed to gather literature on the effect of antioxidants.
In the elderly and any chronic diseases, the declined level of antioxidant molecules enhanced the reactive oxygen species, which in turn deprived the immune system.
Innate antioxidant proteins like sirtuin and sestrin play a vital role in enhancing immunity. Herbal products and holistic approaches can also be alternative solutions for everyday life to boost the immune system by improving the redox balance in COVID-19 attack. This review analyzed the counteractive effect of alternative therapy to boost the immune system against the magnitude of the COVID-19 pandemic.
本综述分析了全球和印度 COVID-19 大流行的规模，以及使用天然和先天免疫增强分子来对抗其影响的措施。本研究关注两个阶段：第一阶段关注流行程度，第二阶段关注抗氧化剂（天然化合物）对 SARS-CoV-2 的影响。
从世界卫生组织（WHO）报告、媒体、卫生部和家庭福利部（MoHFW）报告、报纸以及国家疾病控制中心（NCDC）获得流行率、死亡率和合并症的规模数据。从 PubMed 以及其他网站/期刊和数据库中获取有关抗氧化剂作用的文献。
在老年人和任何慢性疾病中，抗氧化分子水平的下降增强了活性氧，进而剥夺了免疫系统。
先天抗氧化蛋白，如 Sirtuin 和 Sestrin，在增强免疫方面发挥着至关重要的作用。草药产品和整体方法也可以作为日常生活中的替代解决方案，通过改善氧化还原平衡来增强免疫系统，从而对抗 COVID-19 攻击的规模。本综述分析了替代疗法对增强免疫系统以对抗 COVID-19 大流行规模的拮抗作用。
