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2020-2021 年期间，在苏丹应对多种紧急情况期间，为应对 cVDPV2 疫情爆发，建立了有效的伙伴关系和国内资源调动。

Effective partnership and in-country resource mobilization in Sudan for cVDPV2 outbreak response amid multiple emergencies in 2020-2021.

机构信息

Polio and Immunization Programmes, Sudan Country Office, World Health Organization, Khartoum, 2234, Sudan.

Federal Ministry of Health, Khartoum, 2234, Sudan.

出版信息

BMC Public Health. 2024 Jan 19;24(1):235. doi: 10.1186/s12889-023-15675-y.

DOI:10.1186/s12889-023-15675-y
PMID:38243167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10799533/
Abstract

BACKGROUND

During 2020 and immediately prior to the COVID-19 pandemic, Sudan was experiencing multiple emergencies including violence, seasonal flooding, and vector-borne disease outbreaks. After more than ten years since its last case of wild poliovirus, Sudan declared a circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreak on 9 August 2020.

METHODS

cVDPV2 outbreak response data and programme documents of the Federal Ministry of Health and WHO were reviewed. Surveillance data was verified through WHO-recommended procedures for detecting and characterizing polioviruses from stool and sewage samples collected from acute flaccid paralysis (AFP) cases and the environment.

RESULTS

This outbreak in Sudan led to a total of 58 confirmed cases of cVDPV2 from 15 of the 18 states. Two nationwide vaccination campaigns were held to increase immunity of children under-five against poliovirus type 2. Funding challenges were overcome by intense additional resource mobilization from in-country sources. The funding gap was bridged from domestic resources (49%) sourced through GPEI partners, and in-country humanitarian funding mechanisms.

CONCLUSIONS

During an outbreak response and challenge of funding shortfall, mobilizing in-country resources is possible through coordinated approaches, regular communication with partners, disaggregation of needs, and matching in-kind and financial support to fill gaps. A cVDPV2 outbreak requires a fast, resourced, and quality response to stop virus circulation.

摘要

背景

2020 年期间以及 COVID-19 大流行之前，苏丹正经历多种紧急情况，包括暴力、季节性洪水和虫媒疾病暴发。在该国上次发生野生脊髓灰质炎病毒病例 10 多年后，苏丹于 2020 年 8 月 9 日宣布发生循环疫苗衍生脊髓灰质炎病毒 2 型（cVDPV2）疫情。

方法

对联邦卫生部和世卫组织的 cVDPV2 疫情应对数据和规划文件进行了审查。通过世卫组织推荐的程序对来自急性弛缓性麻痹（AFP）病例和环境的粪便和污水样本中脊髓灰质炎病毒进行检测和特征分析，对监测数据进行了核实。

结果

此次苏丹疫情共导致 18 个州中的 15 个州报告了 58 例确诊的 cVDPV2 病例。开展了两次全国性疫苗接种运动，以提高五岁以下儿童对脊髓灰质炎病毒 2 型的免疫力。通过从国内来源和国内人道主义供资机制中调集额外资源，克服了供资挑战。通过与合作伙伴定期沟通、对需求进行分类以及匹配实物和资金支持以填补缺口等协调方法，从国内资源（49%）和全球消灭脊灰行动伙伴调集资金，弥合了资金缺口。

结论

在疫情应对和资金短缺的挑战期间，通过协调方法、与合作伙伴定期沟通、需求分类以及匹配实物和资金支持以填补缺口，调集国内资源是有可能的。cVDPV2 疫情需要快速、有资源和高质量的应对措施以阻止病毒传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/98e3030b7970/12889_2023_15675_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/8c9b2345e189/12889_2023_15675_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/15b04301de47/12889_2023_15675_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/2f03a4c82327/12889_2023_15675_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/8a1b40c86829/12889_2023_15675_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/a33f17f0d5c7/12889_2023_15675_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/98e3030b7970/12889_2023_15675_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/8c9b2345e189/12889_2023_15675_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/15b04301de47/12889_2023_15675_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/2f03a4c82327/12889_2023_15675_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/8a1b40c86829/12889_2023_15675_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/a33f17f0d5c7/12889_2023_15675_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bb0/10799533/98e3030b7970/12889_2023_15675_Fig6_HTML.jpg

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