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应对奥罗普切病毒的新威胁:对医疗系统的影响及公共卫生应对措施

Addressing the emerging threat of Oropouche virus: implications and public health responses for healthcare systems.

作者信息

Okesanya Olalekan John, Amisu Blessing Olawumi, Adigun Olaniyi Abideen, Ahmed Mohamed Mustaf, Agboola Abdulmajeed Opeyemi, Kab Tolga, Eshun Gilbert, Ukoaka Bonaventure Michael, Oso Tolutope Adebimpe, Ogaya Jerico Bautista, Lucero-Prisno Don Eliseo

机构信息

Faculty of Medicine, Department of Public Health and Maritime Transport, University of Thessaly, Volos, Greece.

Department of Medical Laboratory Science, Neuropsychiatric Hospital, Abeokuta, Nigeria.

出版信息

Trop Dis Travel Med Vaccines. 2025 Jan 2;11(1):1. doi: 10.1186/s40794-024-00236-x.

Abstract

Oropouche fever is an increasingly significant health concern in tropical and subtropical areas of South and Central America, and is primarily spread by midge vectors. The Oropouche virus (OROV) was first identified in 1955 and has been responsible for numerous outbreaks, particularly in urban environments. Despite its prevalence, the disease is often under-reported, making it difficult to fully understand its impact. OROV typically causes febrile illness characterized by symptoms such as headaches, muscle pain, and, occasionally, neurological issues such as meningitis. The ability of the virus to thrive in both forested and urban areas has raised concerns regarding its potential spread to new regions, particularly in the context of climate change. This paper delves into the epidemiology, clinical features, and transmission patterns of OROV, shedding light on the difficulties in diagnosing and managing the disease. The absence of specific treatments and vaccines highlights the urgent need for continued research and development of targeted public health strategies. Advancements in molecular diagnostics and vector control strategies can mitigate Oropouche fever's impact. However, a comprehensive public health approach involving increased surveillance, public education, and cross-border collaboration is needed, especially as the global climate crisis may expand vector habitats, posing risks to previously unaffected regions.

摘要

奥罗普切热在南美洲和中美洲的热带和亚热带地区日益成为一个重大的健康问题,主要通过蠓类媒介传播。奥罗普切病毒(OROV)于1955年首次被发现,引发了众多疫情,尤其是在城市环境中。尽管其普遍存在,但该疾病的报告往往不足,这使得难以全面了解其影响。OROV通常会引发发热性疾病,其症状包括头痛、肌肉疼痛,偶尔还会出现如脑膜炎等神经系统问题。该病毒在森林和城市地区均能繁衍,这引发了人们对其可能传播到新地区的担忧,特别是在气候变化的背景下。本文深入探讨了OROV的流行病学、临床特征和传播模式,揭示了该疾病诊断和管理方面的困难。由于缺乏特定的治疗方法和疫苗,凸显了持续开展研究和制定针对性公共卫生策略的迫切需求。分子诊断和病媒控制策略的进展可以减轻奥罗普切热的影响。然而,需要一种全面的公共卫生方法,包括加强监测、公众教育和跨境合作,特别是鉴于全球气候危机可能扩大病媒栖息地,给以前未受影响的地区带来风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0701/11694362/7011df55b975/40794_2024_236_Fig1_HTML.jpg

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