Nithya Karnam, Siddaraman Rajaram, Sheelajoice P P, Rajarathinam Mani, Bhopal Chandra Vurimi
Department Of Pharmacology, Vinayaka Missions University, Salem (Deemed to be university), Chinna Seeragapadi, Salem - 636308, Tamilnadu, India.
Department of Pharmacology, VMKV Medical College, Chinna Seeragapadi, Salem - 636308, Tamil Nadu, India.
Bioinformation. 2023 Dec 31;19(12):1173-1178. doi: 10.6026/973206300191173. eCollection 2023.
is a medicinal plant in the Convolvulaceae family. Traditionally, it is used for different ailments in India and in several other countries. It has a variety of pharmacological qualities, including those that aid wound healing, hepato-protection, cardio-protection, anti-diabetic action, asthma, and epilepsy, memory and learning, and neuroprotection. The whole plant is utilized in Ayurvedic medicine to treat neurological disorders, including amnesia, and it is called the brain tonic by them. Therefore, the use of GC-MS in phytochemical research and chemotaxonomic investigations of medicinal plants containing physiologically active components is critical. Hence, the various secondary metabolites from the methanolic extract of were analyzed using GC-MS technique. The methanolic extract of yielded ten compounds. All ten compounds showed the highest number of hits. Those with the highest concentration were chosen to identify the qualitative compound. All compounds are non-toxic. Molecules with specific properties are capable of modulating a variety of proteins, including some enzymes. Thus, these molecules are potential hit-to-lead molecules in preclinical studies.
是旋花科的一种药用植物。传统上,它在印度和其他几个国家用于治疗各种疾病。它具有多种药理特性,包括有助于伤口愈合、肝脏保护、心脏保护、抗糖尿病作用、哮喘、癫痫、记忆和学习以及神经保护等。阿育吠陀医学中使用整株植物来治疗神经系统疾病,包括失忆症,他们称其为脑滋补剂。因此,气相色谱 - 质谱联用技术在含有生理活性成分的药用植物的植物化学研究和化学分类学研究中至关重要。因此,使用气相色谱 - 质谱联用技术分析了[植物名称]甲醇提取物中的各种次生代谢产物。[植物名称]的甲醇提取物产生了十种化合物。所有十种化合物显示出最高的匹配数。选择浓度最高的那些来鉴定定性化合物。所有化合物均无毒。具有特定性质的分子能够调节多种蛋白质,包括一些酶。因此,这些分子在临床前研究中是潜在的从活性分子到先导分子的化合物。