Maidana Daniela, Arroyo-Álvarez Andrea, Arenas-Loriente Andrea, Barreres-Martín Guillermo, Muñoz-Alfonso Carles, Bompart Berroteran Daznia, Esteve Claramunt Francisca, Blanco Del Burgo Regina, Cepas-Guillén Pedro, Garcia-Blas Sergio, Bonanad Clara
INCLIVA-Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, Spain.
Cardiology Department, Hospital Clinic Barcelona, 08036 Barcelona, Spain.
J Clin Med. 2024 Jan 9;13(2):363. doi: 10.3390/jcm13020363.
Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly impacting their prognosis. Inflammation is intricately linked with the aging process and plays a pivotal role in the evolution of atherosclerosis. Emerging anti-inflammatory therapies have shown promise in reducing ischemic events among high-risk populations. This review aims to explore the potential of targeted anti-inflammatory interventions in improving clinical outcomes and the quality of life for older patients with IHD.
心血管（CV）疾病仍然是一项全球性的健康挑战，缺血性心脏病（IHD）是发病和死亡的主要原因。尽管有最佳的药物治疗，但患有IHD的老年患者对复发性缺血事件的易感性增加，这对他们的预后有重大影响。炎症与衰老过程密切相关，在动脉粥样硬化的发展中起关键作用。新兴的抗炎疗法已显示出在高危人群中减少缺血事件的前景。本综述旨在探讨针对性抗炎干预措施在改善老年IHD患者临床结局和生活质量方面的潜力。
