Han Bing, Liang Shukun, Sun Jintao, Tao Hui, Wang Zhenlong, Liu Baosheng, Wang Xiumin, Liu Jie, Wang Jinquan
Key Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, No. 12 Zhong Guan Cun South Street, Haidian District, Beijing 100081, China.
School of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Microorganisms. 2024 Jan 2;12(1):91. doi: 10.3390/microorganisms12010091.
Lactobacilli have played an important role in the gut health of pets. The aim of this research was to study the effects of isolated Lactobacilli (named L11) on the immune, nutrient metabolism, and gut health of cats. Twelve healthy adult cats were randomly assigned into two groups, the control group (CONTROL, = 6, without any probiotics product) and the treatment group (probiotics, = 6, L11 10 CFU/kg feed), while using the same dry diet. On day 28, blood and fecal samples were collected, and the blood biochemical indices, fecal microbiota, short-chain fatty acids (SCFAs), immunological parameters, and odorous substances were separately tested. The triglyceride of the blood was decreased after using L11 ( < 0.05), which could probably alleviate the occurrence of cat obesity to some extent. The sIgA of the feces was increased by 30.1% ( < 0.05), which could enhance the cat's immunity. The abundance of was increased after using L11 ( < 0.05), and the indole and 3-methylindole of the feces were both reduced compared with the control group; 3-methylindole was especially reduced by 67.3% ( < 0.05), which showed that L11 could also improve the intestinal state of cats. Therefore, this research shows that L11 could be a good choice to improve the gut health and immune functions of cats, and it is probably related to the lipid mechanism of cats.
乳酸杆菌在宠物肠道健康中发挥着重要作用。本研究旨在探讨分离出的乳酸杆菌（命名为L11）对猫的免疫、营养代谢和肠道健康的影响。将12只健康成年猫随机分为两组，对照组（CONTROL，n = 6，不使用任何益生菌产品）和治疗组（益生菌组，n = 6，L11 10⁹ CFU/kg饲料），同时使用相同的干饲料。在第28天，采集血液和粪便样本，分别检测血液生化指标、粪便微生物群、短链脂肪酸（SCFAs）、免疫参数和气味物质。使用L11后血液中的甘油三酯降低（P < 0.05），这可能在一定程度上缓解猫肥胖的发生。粪便中的分泌型免疫球蛋白A（sIgA）增加了30.1%（P < 0.05），这可以增强猫的免疫力。使用L11后双歧杆菌属的丰度增加（P < 0.05），与对照组相比，粪便中的吲哚和3-甲基吲哚均减少；3-甲基吲哚尤其减少了67.3%（P < 0.05），这表明L11还可以改善猫的肠道状态。因此，本研究表明L11可能是改善猫肠道健康和免疫功能的良好选择，并且可能与猫的脂质代谢机制有关。
