Amtaghri Smail, Slaoui Miloudia, Eddouks Mohamed
Team of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, BP 509, Boutalamine, Errachidia, 52000, Morocco.
Energy, Materials and Sustainable Development (EMDD) Team- Higher School of Technology-SALE, Center for Water, Natural Resources Environment and Sustainable Development (CERNE2D), Mohammed V University in Rabat, Avenue Ibn Battouta, B.P. 1014, Rabat, 10000, Morocco.
Cardiovasc Hematol Agents Med Chem. 2025;23(1):11-28. doi: 10.2174/0118715257276051240111060414.
The genus has long been used in phytomedicine. The studied parts of species are used as antirheumatic, diuretic, antidotes against poison, anti-erosion, anti-ulcer, and antidiabetic agents, as well as against headache and skin diseases. The objective of the present review was to summarize the phytochemical and pharmacological aspects related to the genus . The results of this literature analysis show that among all the species of the () family, and showed antibacterial activity; and A. articulata have antioxidant activity, A. aretioides and A. articulata have antidiabetic activity, has cytotoxic activity and , and exhibit anti-inflammatory activity. The genus contains saponins, and alkaloids, such as anabasine, anabasamine, lupinine, jaxartinine, and triterpenic sapogenins. The study of 15 plants has identified 70 compounds with an array of pharmacological activities especially antibacterial, antioxidant, antidiabetic, cytotoxic, and anti-inflammatory activities. However, there is a need for further studies on plants before they can be fully used clinically as a potential drug.
该属长期以来一直用于植物医学。该属物种的研究部位用作抗风湿、利尿、解毒、抗侵蚀、抗溃疡和抗糖尿病药物，以及治疗头痛和皮肤病的药物。本综述的目的是总结与该属相关的植物化学和药理学方面。该文献分析结果表明，在爵床科的所有物种中，[具体物种1]和[具体物种2]具有抗菌活性；[具体物种3]和节花马蓝具有抗氧化活性，灰岩马蓝和节花马蓝具有抗糖尿病活性，[具体物种4]具有细胞毒性活性，[具体物种5]和[具体物种6]表现出抗炎活性。该属含有皂苷和生物碱，如假木贼碱、新烟草碱、羽扇豆碱、杰萨廷碱和三萜皂苷元。对15种[该属植物名称]植物的研究已鉴定出70种具有一系列药理活性的化合物，尤其是抗菌、抗氧化、抗糖尿病、细胞毒性和抗炎活性。然而，在[该属植物名称]植物能够作为潜在药物充分用于临床之前，还需要进一步研究。
