Hansen J E, Sue D Y, Oren A, Wasserman K
Am J Cardiol. 1987 Mar 1;59(6):669-74. doi: 10.1016/0002-9149(87)91190-8.
The relation between the increase in oxygen uptake (VO2) and increase in work rate (WR) between unloaded pedaling and maximal work during incremental cycle ergometer exercise was studied in normal men, men with uncomplicated systemic hypertension and ambulatory men with various cardiovascular diseases. The postulation was that impaired peripheral oxygen delivery would reduce the ratio of the oxygen utilized relative to work performed. The ratio of increase in VO2 to increase in WR (delta VO2/delta WR) was relatively constant: 10.29 +/- 1.01 ml/min/W in normal men (n = 54) for exercise 6 to 14 minutes in duration with uniform work increments of 15, 20, 25 or 30 W/min, regardless of age. The value in men with uncomplicated systemic hypertension (n = 24) was not significantly different from that of normal men. However, more than half of the men with peripheral vascular disease (n = 7) or pulmonary vascular disease (n = 5) or men who had electrocardiographic abnormalities during exercise (n = 39) had a significantly lower delta VO2/delta WR, 8.29 +/- 1.17 ml/min/W (p less than 0.05) especially evident as maximal work rates were approached. Thus, delta VO2/delta WR during incremental exercise testing is predictable for normal men and a reduction in this ratio indicates cardiovascular dysfunction.
在正常男性、无并发症的系统性高血压男性以及患有各种心血管疾病的非卧床男性中，研究了递增式蹬车运动期间从无负荷蹬车到最大负荷运动过程中摄氧量（VO₂）增加与工作率（WR）增加之间的关系。假设是外周氧输送受损会降低所利用的氧与所完成工作的比率。VO₂增加量与WR增加量的比率（δVO₂/δWR）相对恒定：正常男性（n = 54）在持续6至14分钟的运动中，工作率以15、20、25或30 W/min的均匀增量增加，无论年龄如何，该比率为10.29±1.01 ml/min/W。无并发症的系统性高血压男性（n = 24）的值与正常男性的值无显著差异。然而，超过一半的外周血管疾病男性（n = 7）或肺血管疾病男性（n = 5）或运动期间有心电图异常的男性（n = 39）的δVO₂/δWR显著较低，为8.29±1.17 ml/min/W（p<0.05），在接近最大工作率时尤为明显。因此，递增运动测试期间的δVO₂/δWR对正常男性是可预测的，该比率降低表明心血管功能障碍。
