Hammond S R, Yiannikas C
Arch Neurol. 1987 Apr;44(4):382-7. doi: 10.1001/archneur.1987.00520160024009.
Brain-stem auditory evoked responses (BAER) were recorded in a group of 83 patients with a diagnosis of clinically definite or probable multiple sclerosis to assess the relevance of recording contralateral responses simultaneously with ipsilateral responses and to correlate patients disability with the detection of abnormalities. The contralateral responses generally mirrored the ipsilateral responses, but in seven patients the responses differed, mainly involving the presence or absence of wave V. However, contralateral recordings did not contribute significantly to the sensitivity of lesion detection, and their main value was to aid in the recognition of waves when they were not clearly seen in the ipsilateral recordings. The BAER abnormality rates were found to be significantly correlated with disability, and it is suggested that this is an important variable to consider when undertaking or comparing results of BAER studies in patients with multiple sclerosis.
对一组83例临床确诊或疑似多发性硬化症的患者进行脑干听觉诱发电位(BAER)记录,以评估同时记录对侧反应与同侧反应的相关性,并将患者的残疾情况与异常检测结果进行关联。对侧反应通常与同侧反应相似,但有7例患者的反应不同,主要涉及V波的有无。然而,对侧记录对病变检测的敏感性没有显著贡献,其主要价值在于当同侧记录中波形不清晰时,有助于识别波形。发现BAER异常率与残疾情况显著相关,提示在对多发性硬化症患者进行BAER研究或比较结果时,这是一个需要考虑的重要变量。