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静脉注射布美他尼可减轻大手术期间血浆血管加压素浓度的升高。

Intravenous bumetanide attenuates the rise in plasma vasopressin concentrations during major surgical operations.

作者信息

Kaufman L, Bailey P M

出版信息

Br J Clin Pharmacol. 1987 Feb;23(2):237-40. doi: 10.1111/j.1365-2125.1987.tb03036.x.

Abstract

During a study in seven patients on the endocrine response to major surgical procedures under general anaesthesia an incidental finding was that the administration of intravenous bumetanide prior to surgical stimulation led to reduced concentrations of plasma vasopressin (AVP) when compared with a control group of patients.

摘要

在一项针对七名接受全身麻醉下大手术的患者的内分泌反应研究中,一个意外发现是,与对照组患者相比,在手术刺激前静脉注射布美他尼会导致血浆血管加压素(AVP)浓度降低。

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本文引用的文献

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Mechanisms of renal dysfunction during positive end-expiratory pressure ventilation.呼气末正压通气期间肾功能障碍的机制。
J Appl Physiol Respir Environ Exerc Physiol. 1981 Mar;50(3):643-9. doi: 10.1152/jappl.1981.50.3.643.
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Comparison of the acute vascular effects of frusemide and bumetanide.速尿和布美他尼急性血管效应的比较。
Br J Clin Pharmacol. 1986 Apr;21(4):359-64. doi: 10.1111/j.1365-2125.1986.tb05207.x.
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Disposition and response to bumetanide and furosemide.
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