Hassoun J, Gambarelli D, Peragut J C, Toga M
Acta Neuropathol. 1983;62(1-2):31-40. doi: 10.1007/BF00684917.
An ultrastructural study of four pinealomas was carried out to precise eventual specific markers. Dark and clear cells joined with zonulae adherents, extensive and pleiomorphous processes, a complex vacuolar system, and characteristic organelles (lysosome-like structures, clear and dense-core vesicles, vesicle-crowned rodlets and related structures, microtubular sheaves and centriolar derivatives, membranous whorls, fibrous bodies, microtubules, heterogeneous cytoplasmic inclusions) offered a typical pattern. No correlation could be made between the histological and ultrastructural features. The authors stress the ultrastructural similarities between the human tumor cells and the mammalian pineal cells. Pinealomas appeared as a morphological entity distinct from neuronal and astrocytic tumors.
对四个松果体瘤进行了超微结构研究，以确定可能的特异性标志物。深色细胞和透明细胞通过紧密连接相连，具有广泛且形态多样的突起、复杂的液泡系统以及特征性细胞器（溶酶体样结构、清亮和致密核心小泡、泡冠小杆及相关结构、微管束和中心粒衍生物、膜性涡旋、纤维体、微管、异质性胞质内含物）呈现出典型模式。组织学和超微结构特征之间未发现相关性。作者强调人类肿瘤细胞与哺乳动物松果体细胞之间的超微结构相似性。松果体瘤表现为一种与神经元和星形细胞瘤不同的形态学实体。
