Holtzman R, Poulard J B, Bank S, Levin L R, Flint G W, Strauss R J, Margolis I B
Dis Colon Rectum. 1987 Mar;30(3):185-8. doi: 10.1007/BF02554336.
The records of all patients undergoing endoscopic polypectomy between December 1979 and December 1982 were reviewed. One hundred seventy-two patients underwent colonoscopic polypectomy in the absence of carcinoma or inflammatory bowel disease. Of these, the polyp could not be retrieved in 4, and 19 were lost to follow-up. One hundred forty-nine patients underwent subsequent endoscopy from one to four years after the initial polypectomy. Seventy-five (50.3 percent) of the patients developed new polyps. Although 61 of the 75 patients with new polyps were identified in the first two years, new polyps were noted throughout all four years. The presence of multiple polyps on the initial examination was statistically significant in predicting new polyps. The age and sex of the patients, size of the polyps, and the presence of atypia did not identify patients at higher risk for new polyps. The data indicate that new polyps are more likely to develop in patients who had a previous polyp. It would appear that annual examinations should be performed until two successive examinations are negative. Following a second negative examination, reexamination at two- or three-year intervals, unless symptomatic, would appear to be adequate.
回顾了1979年12月至1982年12月期间所有接受内镜下息肉切除术患者的记录。172例患者在无癌或炎症性肠病的情况下接受了结肠镜下息肉切除术。其中，4例息肉未能取出，19例失访。149例患者在首次息肉切除术后1至4年接受了后续内镜检查。75例（50.3%）患者出现了新的息肉。虽然75例有新息肉的患者中有61例在头两年被发现，但在所有四年中都发现了新息肉。初次检查时存在多个息肉在预测新息肉方面具有统计学意义。患者的年龄、性别、息肉大小以及异型增生的存在并不能确定哪些患者发生新息肉的风险更高。数据表明，既往有息肉的患者更有可能出现新的息肉。似乎应该每年进行检查，直到连续两次检查结果为阴性。在第二次检查结果为阴性后，除非有症状，否则每隔两到三年进行一次复查似乎就足够了。
