Brun Adrian, Petit Catherine, Huck Olivier, Bouchard Philippe, Carra Maria Clotilde, Gosset Marjolaine
Unité de recherche URP2496, Biomedical Research In Odontology (BRIO), France - Université Paris Cité, faculté de santé, UFR d'odontologie, Montrouge, France - Hôpital Henri Mondor (AP-HP), service de médecine bucco-dentaire, Créteil, France.
Laboratoire de nanomédecine régénérative, Inserm UMR 1260, CRBS, 1 rue Eugène Boeckel, 67000 Strasbourg, France - Département de parodontologie, faculté de chirurgie dentaire Robert Frank, Strasbourg, France - Hôpitaux universitaires de Strasbourg, pôle de médecine et chirurgie bucco-dentaire, Strasbourg, France.
Med Sci (Paris). 2024 Jan;40(1):35-41. doi: 10.1051/medsci/2023193. Epub 2024 Feb 1.
Epidemiological studies have identified periodontitis as a contributing factor to cardiovascular risk. Periodontitis is a chronic inflammatory disease that affects the tissues supporting the teeth. Although the nature of the association between periodontitis and cardiovascular disease (CVD) remains to be defined, the low-grade systemic inflammation and chronic bacteremia associated with periodontitis appear to be involved in the development of atherosclerosis and associated cardiovascular pathologies. Periodontal treatment has been shown to improve cardiovascular health parameters. A bidirectional preventive approach, involving the management of both periodontitis and cardiovascular risk factors, could lead to a reduction in morbidity and mortality related to cardiovascular disease.
流行病学研究已将牙周炎确定为心血管风险的一个促成因素。牙周炎是一种影响牙齿支持组织的慢性炎症性疾病。尽管牙周炎与心血管疾病（CVD）之间关联的性质仍有待确定，但与牙周炎相关的低度全身炎症和慢性菌血症似乎参与了动脉粥样硬化及相关心血管病变的发展。牙周治疗已被证明可改善心血管健康参数。一种涉及牙周炎和心血管危险因素管理的双向预防方法，可能会降低与心血管疾病相关的发病率和死亡率。
