Kraemer K H, Greene M H
Dermatol Clin. 1985 Apr;3(2):225-37.
Familial dysplastic nevus syndrome is an autosomal-dominant precursor of hereditary melanoma in which individuals have clinically and histologically distinctive nevi and a markedly increased risk for development of melanoma. Dysplastic nevi also are found in sporadic forms. Classification of the condition of the patient and proper management including regular examination of nevi can help to determine the risk of melanoma and minimize the potential for neoplastic progression.
家族性发育异常痣综合征是遗传性黑色素瘤的常染色体显性前驱疾病，患者有临床和组织学上独特的痣，且患黑色素瘤的风险显著增加。发育异常痣也有散发性形式。对患者病情进行分类并进行适当管理，包括定期检查痣，有助于确定黑色素瘤风险并将肿瘤进展的可能性降至最低。
