Jahani-Sherafat Somayeh, Taghavi Hooman, Asri Nastaran, Rezaei Tavirani Mostafa, Razzaghi Zahra, Rostami-Nejad Mohammad
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Gastroenterol Hepatol Bed Bench. 2023;16(4):386-393. doi: 10.22037/ghfbb.v16i4.2687.
Maintaining a healthy balance between commensal, and pathogenic bacteria within the gut microbiota is crucial for ensuring the overall health, and well-being of the host. In fact, by affecting innate, and adaptive immune responses, the gut microbiome plays a key role in maintaining intestinal homeostasis and barrier integrity. Dysbiosis is the loss of beneficial microorganisms and the growth of potentially hazardous microorganisms in a microbial community, which has been linked to numerous diseases. As the primary inducer of circadian rhythm, light can influence the human intestinal microbiome. Photobiomodulation therapy (PBMT), which is the use of red (630-700 nm), and near-infrared light (700 and 1200 nm), can stimulate healing, relieve pain, and reduce inflammation, and affect the circadian rhythm and gut microbiome beneficially. Our focus in this paper is on the effects of PBMT on gut microbiota, to provide an overview of how it can help control gut microbiota dysbiosis-related disorders.
在肠道微生物群中维持共生菌和病原菌之间的健康平衡，对于确保宿主的整体健康和幸福至关重要。事实上，通过影响先天性和适应性免疫反应，肠道微生物群在维持肠道稳态和屏障完整性方面发挥着关键作用。生态失调是指微生物群落中有益微生物的丧失和潜在有害微生物的生长，这与多种疾病有关。作为昼夜节律的主要诱导因素，光可以影响人类肠道微生物群。光生物调节疗法（PBMT），即使用红色（630-700纳米）和近红外光（700和1200纳米），可以刺激愈合、缓解疼痛和减轻炎症，并对昼夜节律和肠道微生物群产生有益影响。本文我们关注的是PBMT对肠道微生物群的影响，以概述其如何有助于控制与肠道微生物群失调相关的疾病。
