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中国股骨颈骨折早期髋关节置换术的趋势和获益:一项全国队列研究。

Trends and benefits of early hip arthroplasty for femoral neck fracture in China: a national cohort study.

机构信息

Department of Orthopedics.

Tibet Autonomous Region People's Hospital, Lhasa, Tibet, People's Republic of China.

出版信息

Int J Surg. 2024 Mar 1;110(3):1347-1355. doi: 10.1097/JS9.0000000000000794.

Abstract

BACKGROUND

Limited studies have examined the benefits of early arthroplasty within 48 h from admission to surgery for femoral neck fractures (FNFs). Using the national inpatient database, the authors aimed to investigate the trends in early arthroplasty within 48 h for FNFs in China and to assess its effect on in-hospital complications and 30-day readmission patterns.

MATERIALS AND METHODS

This was a retrospective cohort study. Patients receiving primary total hip arthroplasty (THA) or hemiarthroplasty (HA) for FNFs in the Hospital Quality Monitoring System between 2013 and 2019 were included. After adjusting for potential confounders with propensity score matching, a logistic regression model was performed to compare the differences in in-hospital complications [i.e. in-hospital death, pulmonary embolism, deep vein thrombosis (DVT), wound infection, and blood transfusion], rates and causes of 30-day readmission between early and delayed arthroplasty.

RESULTS

During the study period, the rate of early THA increased from 18.0 to 19.9%, and the rate of early HA increased from 14.7 to 18.4% ( P <0.001). After matching, 11 731 pairs receiving THA and 13 568 pairs receiving HA were included. Compared with delayed THA, early THA was associated with a lower risk of pulmonary embolism [odds ratio (OR) 0.51, 95% CI: 0.30-0.88], DVT (OR 0.59, 95% CI: 0.50-0.70), blood transfusion (OR 0.62, 95% CI: 0.55-0.70), 30-day readmission (OR 0.82, 95% CI: 0.70-0.95), and venous thromboembolism-related readmission (OR 0.50, 95% CI: 0.34-0.74). Similarly, early HA was associated with a lower risk of DVT (OR 0.70, 95% CI: 0.61-0.80) and blood transfusion (OR 0.74, 95% CI: 0.68-0.81) than delayed HA.

CONCLUSION

Despite a slight increase, the rate of early arthroplasty remained at a low level in China. Given that early arthroplasty can significantly improve prognosis, more efforts are needed to optimize the procedure and shorten the time to surgery.

摘要

背景

仅有少数研究调查了股骨颈骨折(FNF)患者入院后 48 小时内进行早期关节置换术的获益。本研究利用全国住院患者数据库,旨在调查中国 FNF 患者早期(48 小时内)关节置换术的趋势,并评估其对住院并发症和 30 天再入院模式的影响。

材料和方法

这是一项回顾性队列研究。纳入 2013 年至 2019 年期间在医院质量监测系统中接受初次全髋关节置换术(THA)或半髋关节置换术(HA)治疗 FNF 的患者。采用倾向评分匹配调整潜在混杂因素后,采用 logistic 回归模型比较早期和延迟关节置换术在住院并发症[即住院死亡、肺栓塞、深静脉血栓形成(DVT)、伤口感染和输血]、30 天再入院率和再入院原因方面的差异。

结果

在研究期间,早期 THA 的比例从 18.0%增加到 19.9%,早期 HA 的比例从 14.7%增加到 18.4%(P<0.001)。匹配后,纳入 11731 对接受 THA 和 13568 对接受 HA 的患者。与延迟 THA 相比,早期 THA 与较低的肺栓塞风险相关[比值比(OR)0.51,95%可信区间:0.30-0.88]、DVT(OR 0.59,95%可信区间:0.50-0.70)、输血(OR 0.62,95%可信区间:0.55-0.70)、30 天再入院(OR 0.82,95%可信区间:0.70-0.95)和静脉血栓栓塞相关再入院(OR 0.50,95%可信区间:0.34-0.74)。同样,早期 HA 与较低的 DVT(OR 0.70,95%可信区间:0.61-0.80)和输血(OR 0.74,95%可信区间:0.68-0.81)风险相关。

结论

尽管比例略有增加,但中国早期关节置换术的比例仍处于较低水平。鉴于早期关节置换术可显著改善预后,需要进一步努力优化手术流程并缩短手术时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d5/10942226/79acb4eefe86/js9-110-1347-g001.jpg

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