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The emerging role of JAK inhibitors in ovarian cancer: new kids on the block?

作者信息

Al-Bataineh Rania, Al Sharie Ahmed H, Altal Omar F

机构信息

Faculty of Medicine.

Department of Pathology and Microbiology.

出版信息

Ann Med Surg (Lond). 2024 Jan 3;86(2):631-634. doi: 10.1097/MS9.0000000000001591. eCollection 2024 Feb.

DOI:10.1097/MS9.0000000000001591
PMID:38333311
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10849448/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0461/10849448/cdfc7653caf9/ms9-86-0631-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0461/10849448/cdfc7653caf9/ms9-86-0631-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0461/10849448/cdfc7653caf9/ms9-86-0631-g001.jpg

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本文引用的文献

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CA Cancer J Clin. 2023 Jan;73(1):17-48. doi: 10.3322/caac.21763.
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Properties of FDA-approved small molecule protein kinase inhibitors: A 2023 update.FDA 批准的小分子蛋白激酶抑制剂的特性:2023 年更新。
Pharmacol Res. 2023 Jan;187:106552. doi: 10.1016/j.phrs.2022.106552. Epub 2022 Nov 17.
3
Inhibition of Tumor Microenvironment Cytokine Signaling Sensitizes Ovarian Cancer Cells to Antiestrogen Therapy.抑制肿瘤微环境细胞因子信号传导可使卵巢癌细胞对抗雌激素治疗敏感。
Cancers (Basel). 2022 Sep 26;14(19):4675. doi: 10.3390/cancers14194675.
4
Worldwide Burden, Risk Factors, and Temporal Trends of Ovarian Cancer: A Global Study.全球卵巢癌负担、风险因素及时间趋势:一项全球研究。
Cancers (Basel). 2022 Apr 29;14(9):2230. doi: 10.3390/cancers14092230.
5
JAK/STAT Signaling: Molecular Targets, Therapeutic Opportunities, and Limitations of Targeted Inhibitions in Solid Malignancies.JAK/STAT信号传导:实体恶性肿瘤中的分子靶点、治疗机遇及靶向抑制的局限性
Front Pharmacol. 2022 Mar 24;13:821344. doi: 10.3389/fphar.2022.821344. eCollection 2022.
6
Erastin Reverses ABCB1-Mediated Docetaxel Resistance in Ovarian Cancer.埃拉斯汀逆转卵巢癌中ABCB1介导的多西他赛耐药性。
Front Oncol. 2019 Dec 19;9:1398. doi: 10.3389/fonc.2019.01398. eCollection 2019.
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Ovarian cancer: Current status and strategies for improving therapeutic outcomes.卵巢癌:改善治疗效果的现状和策略。
Cancer Med. 2019 Nov;8(16):7018-7031. doi: 10.1002/cam4.2560. Epub 2019 Sep 27.
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Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer.基于基因组的联合筛选鉴定出抗凋亡基因,其可作为卵巢癌化疗耐药的靶向治疗新靶点。
Mol Cancer Res. 2019 Nov;17(11):2281-2293. doi: 10.1158/1541-7786.MCR-18-1243. Epub 2019 Aug 28.
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