Tomazin Rok, Matos Tadeja
Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Diagnostics (Basel). 2024 Jan 29;14(3):288. doi: 10.3390/diagnostics14030288.
Many infectious diseases are transmitted via the air and are, therefore, particularly difficult to combat. These infections include various invasive mycoses caused by molds. The usual route of infection is the inhalation of conidia. In hospitals, infection can also occur through the deposition of conidia in otherwise sterile anatomical sites during surgical and other invasive procedures. Therefore, knowledge of airborne mold concentrations can lead to measures to protect patients from fungal infections. The literature on this topic contains insufficient and sometimes ambiguous information. This is evidenced by the fact that there are no international recommendations or guidelines defining the methodology of air sampling and the interpretation of the results obtained. Surgical departments, intensive care units and medical mycology laboratories are, therefore, left to their own devices, leading to significant differences in the implementation of mycological surveillance in hospitals. The aim of this mini-review is to provide an overview of the current methods of air sampling and interpretation of results used in medical mycology laboratories.
许多传染病通过空气传播，因此特别难以防治。这些感染包括由霉菌引起的各种侵袭性真菌病。通常的感染途径是吸入分生孢子。在医院里，感染也可能通过在手术和其他侵入性操作过程中，分生孢子沉积在原本无菌的解剖部位而发生。因此，了解空气中霉菌的浓度有助于采取措施保护患者免受真菌感染。关于这一主题的文献资料不足，有时还含糊不清。这一点从没有国际建议或指南来定义空气采样方法和所得结果的解释就可以得到证明。因此，外科科室、重症监护病房和医学真菌学实验室只能自行其是，导致医院真菌学监测的实施存在显著差异。本综述的目的是概述医学真菌学实验室目前使用的空气采样方法和结果解释。
