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中华人民共和国崇明岛的乙型肝炎病毒与原发性肝癌

Hepatitis B virus and primary liver cancer on Chongming Island, People's Republic of China.

作者信息

Tu J T, Gao R N, Zhang D H, Gu B C

出版信息

Natl Cancer Inst Monogr. 1985 Dec;69:213-5.

PMID:3834335
Abstract

Data on potential risk factors for primary liver cancer (PLC), including hepatitis B virus (HBV) infection, contaminated drinking water, maize consumption, and use of tobacco and alcohol were collected from 12,222 males over 40 years of age living on Chongming Island, a high-risk area for PLC. During the first 3 years of follow-up (1980-82), 70 deaths from this disease occurred among study subjects. Preliminary results indicate that HBV carriers were 6.7 times more likely to die of PLC than were noncarriers (P less than .05). No association was found between PLC and alcohol consumption. More data are needed for evaluation of the relationships between cigarette smoking, maize consumption, contaminated drinking water, and PLC on Chongming Island.

摘要

从崇明岛(原发性肝癌高发地区)40岁以上的12222名男性中收集了原发性肝癌(PLC)潜在风险因素的数据,包括乙肝病毒(HBV)感染、饮用受污染的水、食用玉米以及烟草和酒精的使用情况。在随访的前3年(1980 - 1982年),研究对象中有70人死于该疾病。初步结果表明,HBV携带者死于PLC的可能性是非携带者的6.7倍(P < 0.05)。未发现PLC与饮酒之间存在关联。需要更多数据来评估崇明岛上吸烟、食用玉米、饮用受污染的水与PLC之间的关系。

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