Ingólfsdóttir K, Bloomfield S F, Hylands P J
Antimicrob Agents Chemother. 1985 Aug;28(2):289-92. doi: 10.1128/AAC.28.2.289.
Antimicrobial screening of several lichen species and subsequent isolation and structure elucidation of active compounds revealed that the hydrolysis products of certain lichen metabolites, i.e., depsides, were active against gram-negative bacteria and fungi as well as gram-positive bacteria. The active constituents isolated from Stereocaulon alpinum and Peltigera aphthosa were identified, respectively, as methyl beta-orsellinate and a mixture of methyl and ethyl orsellinates. MIC determinations indicated that activity of these compounds was superior to that of the commonly used preservative agents methyl and propyl p-hydroxybenzoates and was of the same order as that of chlorocresol.
对几种地衣物种进行抗菌筛选，并随后对活性化合物进行分离和结构解析，结果表明某些地衣代谢产物（即缩酚酸）的水解产物对革兰氏阴性菌、真菌以及革兰氏阳性菌均具有活性。从高山石蕊和地卷中分离出的活性成分分别被鉴定为β-苔色酸甲酯以及苔色酸甲酯和乙酯的混合物。最低抑菌浓度测定表明，这些化合物的活性优于常用防腐剂对羟基苯甲酸甲酯和对羟基苯甲酸丙酯，与氯甲酚的活性相当。
