Huovinen P, Mattila T, Kiminki O, Pulkkinen L, Huovinen S, Koskela M, Sunila R, Toivanen P
Antimicrob Agents Chemother. 1985 Aug;28(2):354-6. doi: 10.1128/AAC.28.2.354.
The emergence of trimethoprim (TMP) resistance in fecal flora was compared in patients with urinary tract infection treated with TMP or TMP-sulfamethoxazole. No significant differences were found in the occurrence of TMP-resistant fecal aerobic bacteria in the two treatment groups before and after treatment.
对接受甲氧苄啶(TMP)或甲氧苄啶-磺胺甲恶唑治疗的尿路感染患者粪便菌群中TMP耐药性的出现情况进行了比较。在两个治疗组中,治疗前后粪便需氧菌中TMP耐药菌的发生率没有发现显著差异。