Department of Ophthalmology, Hebei Children's Hospital, Shijiazhuang, 050000, Hebei, China.
Department of Ultrasonic, The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Sci Rep. 2024 Feb 13;14(1):3645. doi: 10.1038/s41598-024-54161-2.
This study aims to investigate the effectiveness of Intense Pulsed Light (IPL) therapy for chalazion treatment while also exploring potential variations in sensitivity among different types of chalazion. A total of 149 patients were selected to receive tobramycin combined with IPL treatment and tobramycin combined with hot compress. The treatment groups were divided into cystic type and granulomatous type according to different clinical manifestations. The course of treatment was 3 weeks. The improvement was based on the ultrasound measurement of the masses reduction of more than 50% or disappearance. In the IPL group, 17 (22.67%) cases were cured, 39 (52.00%) were effective, and 19 (25.33%) were ineffective. This includes: cystic type was cured in 3 (15.79%), effective in 5 (26.32%) cases, ineffective in 11 (57.89%) cases; granulomatous type was cured in 14 (25.00%) cases, effective in 34 (60.71%) cases, ineffective in 8 (14.29%) cases. In the hot compress group, 5 (6.76%) cases were cured, 16 (21.62%) cases were effective and 53 (71.62%) cases were ineffective. The cystic type was cured in 2 (8.00%) cases, effective in 3 (12.00%) cases and ineffective in 20 (80.00%) cases; the granulomatous type was cured in 3 (6.12%) cases, effective in 13 (26.53%) cases and ineffective in 33 (67.35%) cases. The cure rate and efficacy rate of IPL treatment is higher than that of hot compress treatment, the treatment effect of IPL treatment on granulomatous chalazion is better than that on cystic type.
本研究旨在探讨强脉冲光(IPL)疗法治疗霰粒肿的有效性,同时探索不同类型霰粒肿的敏感性差异。共选择 149 例患者接受妥布霉素联合 IPL 治疗和妥布霉素联合热敷治疗。根据不同的临床表现,将治疗组分为囊肿型和肉芽肿型。治疗疗程为 3 周。疗效评价标准为超声测量肿块缩小 50%以上或消失。在 IPL 组中,17 例(22.67%)治愈,39 例(52.00%)有效,19 例(25.33%)无效。其中囊肿型治愈 3 例(15.79%),有效 5 例(26.32%),无效 11 例(57.89%);肉芽肿型治愈 14 例(25.00%),有效 34 例(60.71%),无效 8 例(14.29%)。在热敷组中,5 例(6.76%)治愈,16 例(21.62%)有效,53 例(71.62%)无效。其中囊肿型治愈 2 例(8.00%),有效 3 例(12.00%),无效 20 例(80.00%);肉芽肿型治愈 3 例(6.12%),有效 13 例(26.53%),无效 33 例(67.35%)。IPL 治疗的治愈率和有效率高于热敷治疗,IPL 治疗对肉芽肿性霰粒肿的疗效优于囊肿型。