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巴西里约热内卢动物源性孢子丝菌病 25 周年纪念:孢子丝菌病的当前和未来研究议程。

The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil.

机构信息

Fundação Oswaldo Cruz-Fiocruz, Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Micologia, Rio de Janeiro, RJ, Brasil.

Fundação Oswaldo Cruz-Fiocruz, Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Dermatologia Infecciosa, Rio de Janeiro, RJ, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 2024 Feb 12;119:e230208. doi: 10.1590/0074-02760230208. eCollection 2024.

DOI:10.1590/0074-02760230208
PMID:38359307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10868377/
Abstract

Twenty-five years have passed since the initial observation of endemic zoonotic sporotrichosis in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying the emergence of this mycosis, some progress has been made, including the expansion of a research network in this field and higher visibility of sporotrichosis within government authorities and funding agencies. However, there are still some challenges to curbing the expansion of this disease in the coming years. These include the development of rapid and accurate diagnostic tests, new antifungal drugs, particularly for the treatment of extracutaneous manifestations of sporotrichosis, and more comprehensive care for cats with sporotrichosis. Including these actions in the sporotrichosis research agenda is required so as to change the development of this disease in the years to come.

摘要

自巴西里约热内卢首次观察到地方性动物源性孢子丝菌病以来,已经过去了 25 年。从那时起,这种疾病已经蔓延到整个南美洲。随着这种真菌病的出现,一些进展已经取得,包括在该领域扩大研究网络以及在政府当局和资助机构中提高孢子丝菌病的可见度。然而,在未来几年遏制这种疾病的蔓延仍然存在一些挑战。这些挑战包括开发快速准确的诊断测试、新的抗真菌药物,特别是用于治疗孢子丝菌病的皮肤外表现,以及为患有孢子丝菌病的猫提供更全面的护理。需要将这些行动纳入孢子丝菌病研究议程,以便在未来几年改变这种疾病的发展。

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